CHT Hyperbaric Pharmacology Flashcards
6 cards from real Certified Hyperbaric Technologist Test practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 CHT Hyperbaric Pharmacology flashcards as text
HBO therapy promotes angiogenesis in chronic wounds primarily through:
Answer: Stimulating hypoxia-inducible factor (HIF) pathways during the post-treatment normoxic period
The oscillation between hyperoxia during treatment and relative hypoxia between sessions activates HIF-1α, driving VEGF-mediated angiogenesis.
What is the mechanism by which HBO helps treat carbon monoxide poisoning?
Answer: It accelerates dissociation of CO from hemoglobin by increasing dissolved oxygen
At 3 ATA with 100% O2, the half-life of CO-Hb is reduced from ~5 hours (room air) to ~20 minutes by competitively displacing CO.
Hyperbaric oxygen enhances the killing of anaerobic bacteria by:
Answer: Raising tissue oxygen levels toxic to obligate anaerobes that lack antioxidant enzymes
Obligate anaerobes cannot neutralize reactive oxygen species generated under hyperoxia, making high pO2 directly bactericidal.
Nitroglycerin patches worn during HBO present what risk?
Answer: They may ignite or burn in the oxygen-enriched atmosphere
Transdermal nitroglycerin patches contain flammable materials and must be removed before HBO to prevent fire risk in the oxygen-enriched environment.
Which statement about methylprednisolone and HBO therapy is most accurate?
Answer: Corticosteroids may blunt the angiogenic and wound healing benefits of HBO
Corticosteroids suppress inflammation and may impair the fibroblast proliferation and angiogenesis that HBO therapy aims to promote.
Antineoplastic drug doxorubicin (Adriamycin) is a relative contraindication to HBO because:
Answer: It acts as a free radical generator that synergizes with oxygen toxicity in the lungs
Doxorubicin generates reactive oxygen species, and combined with hyperbaric oxygen, the cumulative free radical load can cause severe pulmonary toxicity.
How this page was made: written with AI tools and published by Nathan Beja, founder of Practice Test Geeks, who is responsible for its content. Exam facts are checked against the official sources listed below. Not reviewed by a subject-matter expert. Editorial policy
Sources & references
Exam facts on this page (fees, format, dates, passing scores) are checked against these official sources; the date is our last check. Editorial policy
- nbdhmt.org — Renewal, eligibility, exam format, passing score, retake policy, score validity, fees, retake fee, test delivery, registration deadline · verified Oct 2026