CDN Renal Pharmacology for Dialysis Nurses 2

Question 1

Heparin is administered at the start of hemodialysis primarily to prevent:

Accepted Answer

Clotting in the extracorporeal circuit

Answer

Access infection

Answer

Hypotension

Answer

Membrane fouling

Question 2

A dialysis patient is prescribed active vitamin D therapy. Which laboratory values must be monitored to prevent complications?

Accepted Answer

Serum calcium and phosphorus

Answer

BUN and creatinine

Answer

Serum potassium and sodium

Answer

Hemoglobin and ferritin

Question 3

Which medication requires dose adjustment or avoidance in dialysis patients due to accumulation of active metabolites that can cause neurological toxicity?

Accepted Answer

Meperidine (Demerol)

Answer

Acetaminophen

Answer

Ibuprofen

Answer

Omeprazole

Question 4

When should phosphate binders be administered to achieve maximum effectiveness?

Accepted Answer

With or immediately after meals

Answer

30 minutes before meals

Answer

At bedtime

Answer

During hemodialysis treatment

Question 5

A dialysis patient on warfarin for atrial fibrillation requires more frequent INR monitoring. Why?

Accepted Answer

Altered protein binding and volume of distribution affect drug levels

Answer

Dialysis removes warfarin from the blood

Answer

Heparin used during dialysis reverses warfarin

Answer

Vitamin K is removed by dialysis

Question 6

What is the rationale for timing the administration of intravenous antibiotics in hemodialysis patients?

Accepted Answer

Antibiotics should be dosed after dialysis to prevent removal by the procedure

Answer

Antibiotics should be given 2 hours before dialysis

Answer

Antibiotics are ineffective in dialysis patients

Answer

Dialysis increases antibiotic bioavailability