Evaluation and Preparation for Transplant Flashcards
7 cards from real CCTC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Evaluation and Preparation for Transplant flashcards as text
Which pulmonary function test value below the threshold typically contraindicates lung transplant evaluation?
Answer: DLCO < 20% predicted
A DLCO below 20% predicted is associated with extremely high post-operative mortality and is generally considered a contraindication to lung transplant.
During pretransplant cardiac evaluation for a kidney transplant candidate, which finding would most likely EXCLUDE the patient from listing?
Answer: Ejection fraction of 35% unresponsive to optimization
Severe left ventricular dysfunction with an EF of 35% that does not improve with medical optimization is a relative-to-absolute contraindication for kidney transplant due to perioperative cardiac risk.
A liver transplant candidate has a MELD-Na score of 28. What does this primarily indicate?
Answer: Higher 90-day mortality risk and greater urgency for transplant
MELD-Na scores reflect 90-day waitlist mortality; higher scores indicate sicker patients who are prioritized for organ allocation.
Which immunological test is performed to detect preformed antibodies against HLA antigens in a transplant candidate?
Answer: Panel Reactive Antibody (PRA) testing
PRA testing identifies the breadth of a candidate's sensitization by detecting preformed anti-HLA antibodies that could cause hyperacute rejection.
What is the primary purpose of a virtual crossmatch in transplant evaluation?
Answer: To compare donor HLA typing against recipient antibody profiles without mixing actual cells
Virtual crossmatch uses donor HLA typing and recipient DSA data to predict crossmatch results without requiring physical serum and cells, enabling faster organ placement.
A kidney transplant candidate is found to have significant peripheral vascular disease on evaluation. What is the most important implication for surgical planning?
Answer: Vascular surgeons must assess iliac vessel patency before listing
Peripheral vascular disease affecting iliac vessels can jeopardize anastomosis success; vascular assessment is mandatory to determine surgical feasibility.
Which nutritional parameter is most commonly assessed and optimized before listing a patient for liver transplant?
Answer: Sarcopenia assessment via CT or muscle function testing
Sarcopenia, detected via CT cross-sectional muscle area or functional testing, is strongly associated with post-transplant mortality and is a primary nutritional target pre-listing.