Sepsis and MODS Flashcards

According to Surviving Sepsis Campaign guidelines, broad-spectrum antibiotics should be administered within what timeframe for patients with septic shock?

Answer: Within 1 hour of recognition

Antibiotics should be given within 1 hour of recognizing septic shock to reduce mortality.

A patient in septic shock remains hypotensive after adequate fluid resuscitation. Which vasopressor is the recommended first-line agent?

Answer: Norepinephrine

Norepinephrine is the first-line vasopressor for septic shock per current guidelines.

Which lactate value best indicates tissue hypoperfusion and increased mortality risk in sepsis?

Answer: Greater than 2 mmol/L

A lactate above 2 mmol/L signals tissue hypoperfusion and warrants resuscitation.

The initial recommended crystalloid fluid bolus for sepsis-induced hypoperfusion is at least:

Answer: 30 mL/kg

At least 30 mL/kg of IV crystalloid is recommended within the first 3 hours.

Which crystalloid is generally preferred for large-volume resuscitation in sepsis to avoid hyperchloremic acidosis?

Answer: Balanced solutions like lactated Ringer's

Balanced crystalloids are favored over normal saline to reduce hyperchloremic metabolic acidosis.

A septic patient develops new confusion, increased respiratory rate, and a SBP of 88 mmHg. Using qSOFA, how many criteria are met?

Answer: 3

Altered mentation, RR ≥22, and SBP ≤100 are all three qSOFA criteria.

Which adjunctive therapy is recommended for septic shock patients who remain hemodynamically unstable despite fluids and vasopressors?

Answer: IV hydrocortisone

IV hydrocortisone is suggested for refractory septic shock requiring ongoing vasopressors.