CBRN Pharmacology & Medication Management

Question 1

Which topical antimicrobial agent is most commonly used for burn wound care due to its broad-spectrum coverage and ability to penetrate eschar?

Accepted Answer

Silver sulfadiazine (Silvadene)

Answer

Silver sulfadiazine is the most widely used topical agent in burn care due to its broad-spectrum antimicrobial properties and ability to penetrate burn eschar.

Question 2

A patient with a major burn is receiving morphine for pain control. Which side effect is MOST concerning in a patient with a concurrent inhalation injury?

Accepted Answer

Respiratory depression

Answer

Respiratory depression is the most dangerous opioid side effect in burn patients with inhalation injuries, as their respiratory function is already compromised.

Question 3

Mafenide acetate (Sulfamylon) is preferred over silver sulfadiazine in which clinical situation?

Accepted Answer

Burns with suspected deep infection requiring eschar penetration

Answer

Mafenide acetate penetrates eschar more effectively than silver sulfadiazine, making it the preferred agent when deep infection is suspected or confirmed.

Question 4

Which medication is used to attenuate the hypermetabolic response in burn patients by blocking catecholamine effects?

Accepted Answer

Propranolol

Answer

Propranolol, a non-selective beta-blocker, attenuates the hypermetabolic response in burn patients by blocking the effects of excess catecholamines released after major burns.

Question 5

High-dose intravenous Vitamin C (ascorbic acid) is administered early in major burn resuscitation primarily to:

Accepted Answer

Reduce lipid peroxidation and decrease resuscitation fluid requirements

Answer

High-dose Vitamin C (66 mg/kg/hr for 24 hours) acts as an antioxidant, reducing free radical-mediated lipid peroxidation and capillary leak, thereby decreasing fluid resuscitation requirements.

(CBRN) Certified Burn Registered Nurse Practice Test

(CBRN) Certified Burn Registered Nurse Practice Test

CBRN Pharmacology & Medication Management