CBRN Burn Pathophysiology & Wound Care Management 2

Question 1

Which zone of Jackson's burn model contains irreversibly damaged, necrotic tissue at the burn center?

Accepted Answer

Zone of coagulation

Answer

The zone of coagulation is the innermost, most damaged area where protein coagulation causes irreversible cell death.

Question 2

A patient sustains a burn injury. Which mediator is primarily responsible for the early increase in capillary permeability?

Accepted Answer

Histamine

Answer

Histamine released from mast cells causes the initial increase in capillary permeability within the first 30 minutes post-burn.

Question 3

During the ebb phase of the burn stress response, which hemodynamic finding is most expected?

Accepted Answer

Decreased cardiac output

Answer

The ebb phase (first 48 hours) is characterized by decreased cardiac output, hypoperfusion, and reduced metabolic rate.

Question 4

A full-thickness burn wound appears pale and leathery with no blistering. What best explains the absence of pain in this wound?

Accepted Answer

Destruction of nerve endings in the dermis

Answer

Full-thickness burns destroy nerve endings, causing insensitivity to pain in the wound itself.

Question 5

Silver sulfadiazine (Silvadene) is contraindicated in which patient population?

Accepted Answer

Neonates and premature infants

Answer

Silver sulfadiazine is contraindicated in neonates and premature infants due to the risk of kernicterus from sulfonamide displacement of bilirubin.

(CBRN) Certified Burn Registered Nurse Practice Test