A 50-year-old male is admitted with hypertensive emergency (BP 220/130 mmHg) and new onset confusion. Fundoscopy reveals papilledema. Which medication and target BP reduction are most appropriate in the first hour?
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A
Oral amlodipine, reduce BP to normal within 1 hour
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B
IV labetalol or nicardipine, reduce MAP by no more than 25% in the first hour
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C
IV nitroprusside, normalize BP within 30 minutes
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D
Oral clonidine, reduce BP by 50% within 2 hours