Canadian Entry To Practice Sterile Products Flashcards

What does the term 'first air' refer to in aseptic technique?

Answer: Uninterrupted HEPA-filtered air directly from the filter face

First air is the HEPA-filtered air flowing directly from the filter uninterrupted by any object, and critical sites must always be exposed to first air.

When preparing a chemotherapy agent, which personal protective equipment (PPE) is specifically required beyond standard garbing?

Answer: Double chemotherapy-tested gloves and a closed-front gown

Preparation of hazardous chemotherapy requires double chemotherapy-tested gloves and a closed-front, cuffed, low-permeability gown to prevent skin absorption.

A pharmacy technician notices that a laminar airflow workbench alarm is sounding and airflow is compromised. What is the correct action?

Answer: Stop compounding and quarantine all preparations made during the malfunction

All preparations made during a compromised airflow event must be quarantined and investigated before any release, as sterility cannot be assured.

Which parameter is most important to verify when preparing a large-volume parenteral (LVP) admixture?

Answer: Final drug concentration, volume, and compatibility

Verifying final concentration, total volume, and drug-drug/drug-solution compatibility ensures the LVP admixture is safe and effective for the patient.

What is the recommended alcohol concentration for disinfecting surfaces and critical sites in sterile compounding?

Answer: 70% isopropyl alcohol

70% isopropyl alcohol is most effective for surface disinfection because it denatures proteins while maintaining sufficient moisture contact time to kill microorganisms.

In Canada, which organization publishes the Model Standards for Pharmacy Compounding of Hazardous Drugs?

Answer: NAPRA

NAPRA (National Association of Pharmacy Regulatory Authorities) publishes the Model Standards for Pharmacy Compounding of Hazardous Drugs adopted by provincial colleges.