Board Certified Ophthalmologist Uveitis and Ocular Inflammation

Question 1

A 25-year-old male presents with acute anterior uveitis and lower back pain. HLA-B27 testing is positive. Which condition is most likely associated with this presentation?

Accepted Answer

Ankylosing spondylitis

Answer

HLA-B27-positive acute anterior uveitis with sacroiliitis or lower back pain is classically associated with ankylosing spondylitis, a seronegative spondyloarthropathy.

Question 2

What is the classic appearance of keratic precipitates (KPs) in granulomatous uveitis?

Accepted Answer

Large, greasy 'mutton-fat' KPs in the inferior cornea

Answer

Granulomatous uveitis is characterized by large, greasy 'mutton-fat' KPs that accumulate in the inferior cornea due to aqueous convection currents.

Question 3

A patient with intermediate uveitis shows 'snowballs' in the vitreous and 'snowbanking' over the pars plana. Which condition is most likely?

Accepted Answer

Pars planitis

Answer

Pars planitis is a form of idiopathic intermediate uveitis characterized by vitreous snowballs and snowbank (exudate) formation overlying the pars plana.

Question 4

Which class of medication is the first-line treatment for non-infectious uveitis?

Accepted Answer

Corticosteroids

Answer

Corticosteroids—topical, periocular, or systemic—are the first-line agents for non-infectious uveitis due to their potent and rapid anti-inflammatory effect.

Question 5

A patient presents with bilateral granulomatous panuveitis, sunset glow fundus, vitiligo, poliosis, and alopecia. What is the most likely diagnosis?

Accepted Answer

Vogt-Koyanagi-Harada syndrome

Answer

VKH syndrome is characterized by bilateral granulomatous uveitis, sunset glow fundus from choroidal depigmentation, and extraocular findings including vitiligo, poliosis, and alopecia.

Board Certified Ophthalmologist Practice Test

Board Certified Ophthalmologist Practice Test

Board Certified Ophthalmologist Uveitis and Ocular Inflammation