Biochemistry Lipids and Membranes 2

Question 1

Beta-oxidation of fatty acids occurs primarily in which cellular compartment?

Accepted Answer

Mitochondrial matrix

Answer

Cytosol

Answer

Smooth ER

Answer

Peroxisome only

Question 2

Carnitine plays an essential role in fatty acid oxidation by:

Accepted Answer

Transporting long-chain fatty acyl groups across the inner mitochondrial membrane

Answer

Activating fatty acids to acyl-CoA in the cytosol

Answer

Serving as a coenzyme for beta-oxidation enzymes

Answer

Regenerating CoA from acetyl-CoA

Question 3

During fatty acid synthesis, malonyl-CoA is formed from acetyl-CoA by which enzyme?

Accepted Answer

Acetyl-CoA carboxylase (ACC)

Answer

Fatty acid synthase (FAS)

Answer

HMG-CoA reductase

Answer

Citrate lyase

Question 4

Fatty acid synthesis occurs in which cellular compartment?

Accepted Answer

Cytosol

Answer

Mitochondrial matrix

Answer

Peroxisome

Answer

Smooth ER

Question 5

Ketone bodies are produced in the liver primarily from excess:

Accepted Answer

Acetyl-CoA

Answer

Glucose

Answer

Amino acids

Answer

Glycerol

Question 6

Which enzyme is the rate-limiting step in cholesterol biosynthesis?

Accepted Answer

HMG-CoA reductase

Answer

Squalene synthase

Answer

HMG-CoA synthase

Answer

Lanosterol synthase