BCPS Medication Safety & Regulatory Compliance 4

Question 1

Under the Occupational Safety and Health Administration (OSHA) Hazard Communication Standard, which document must be accessible to pharmacy staff handling hazardous drugs and contains information on safe handling and spill cleanup?

Accepted Answer

Safety Data Sheet (SDS)

Answer

OSHA requires Safety Data Sheets (formerly MSDS) to be accessible for all hazardous chemicals including antineoplastic drugs, detailing PPE, spill response, and health hazards.

Question 2

A hospital pharmacist identifies that a prescriber has written methotrexate 'daily' for rheumatoid arthritis instead of 'weekly.' This is a classic prescribing error because methotrexate for RA is dosed:

Accepted Answer

Once weekly

Answer

Methotrexate for RA and other non-oncologic indications is prescribed once weekly; daily dosing causes severe toxicity including myelosuppression and mucositis.

Question 3

Which USP chapter sets environmental monitoring and clean room classification standards for sterile compounding?

Accepted Answer

USP <797>

Answer

USP <797> governs sterile compounding including ISO classification of cleanrooms, air quality monitoring, and garbing requirements.

Question 4

A pharmacist notices that the automated dispensing cabinet (ADC) override feature is being used frequently to access medications before pharmacist verification. What is the PRIMARY concern with this practice?

Accepted Answer

Medications may be administered without pharmacist review for appropriateness, interactions, or dosing errors

Answer

ADC overrides bypass pharmacist order verification, removing the critical safety check for dose, indication, interactions, and allergies before patient administration.

Question 5

Which federal law requires community pharmacies to offer counseling to Medicaid patients on new prescriptions and mandates prospective drug utilization review (Pro-DUR)?

Accepted Answer

Omnibus Budget Reconciliation Act (OBRA) of 1990

Answer

OBRA '90 mandates prospective DUR and pharmacist counseling offers for new and refill prescriptions dispensed to Medicaid beneficiaries.

(BCPS) Board Certified Pharmacotherapy Specialist Practice Test

(BCPS) Board Certified Pharmacotherapy Specialist Practice Test

BCPS Medication Safety & Regulatory Compliance 4