BCACP Infectious Disease and Immunization Management 5

Question 1

A pharmacist reviews a patient's chart and notes MRSA bacteremia. Which antibiotic is the drug of choice?

Accepted Answer

Vancomycin

Answer

Vancomycin remains the standard of care for MRSA bacteremia in ambulatory and inpatient settings.

Question 2

Which dosing strategy for vancomycin is currently recommended by updated ASHP/IDSA/SIDP consensus guidelines?

Accepted Answer

AUC/MIC-guided monitoring targeting AUC 400–600 mg·h/L

Answer

The 2020 ASHP/IDSA/SIDP consensus guideline recommends AUC/MIC-guided vancomycin monitoring to optimize efficacy and minimize nephrotoxicity.

Question 3

A patient with a penicillin allergy documented as 'rash' needs treatment for community-acquired pneumonia. What is the most appropriate approach?

Accepted Answer

Perform allergy risk stratification; a low-risk history may allow use of cephalosporins

Answer

A non-severe penicillin allergy history (e.g., rash) warrants risk stratification; cross-reactivity with cephalosporins is low and cephalosporins can often be used safely.

Question 4

Which immunization is specifically recommended for adults asplenic or with functional asplenia to prevent encapsulated organism infections?

Accepted Answer

PCV15 or PCV20 followed by PPSV23, plus meningococcal vaccines (MenACWY and MenB)

Answer

Asplenic patients are at high risk for infections with encapsulated organisms and require pneumococcal, meningococcal (MenACWY and MenB), and Hib vaccines.

Question 5

A clinic patient tests positive for HCV RNA. What is the preferred treatment regimen for treatment-naïve, non-cirrhotic genotype 1a HCV?

Accepted Answer

Glecaprevir/pibrentasvir for 8 weeks

Answer

Glecaprevir/pibrentasvir (Mavyret) for 8 weeks is a pangenotypic, guideline-recommended option for treatment-naïve non-cirrhotic HCV patients.

BCACP - Board Certified Ambulatory Care Pharmacist Exam Practice Test

BCACP - Board Certified Ambulatory Care Pharmacist Exam Practice Test

BCACP Infectious Disease and Immunization Management 5