Infectious Disease and Immunization Management Flashcards
7 cards from real BCACP practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Infectious Disease and Immunization Management flashcards as text
A pharmacist reviews a patient's chart and notes MRSA bacteremia. Which antibiotic is the drug of choice?
Answer: Vancomycin
Vancomycin remains the standard of care for MRSA bacteremia in ambulatory and inpatient settings.
Which dosing strategy for vancomycin is currently recommended by updated ASHP/IDSA/SIDP consensus guidelines?
Answer: AUC/MIC-guided monitoring targeting AUC 400–600 mg·h/L
The 2020 ASHP/IDSA/SIDP consensus guideline recommends AUC/MIC-guided vancomycin monitoring to optimize efficacy and minimize nephrotoxicity.
A patient with a penicillin allergy documented as 'rash' needs treatment for community-acquired pneumonia. What is the most appropriate approach?
Answer: Perform allergy risk stratification; a low-risk history may allow use of cephalosporins
A non-severe penicillin allergy history (e.g., rash) warrants risk stratification; cross-reactivity with cephalosporins is low and cephalosporins can often be used safely.
Which immunization is specifically recommended for adults asplenic or with functional asplenia to prevent encapsulated organism infections?
Answer: PCV15 or PCV20 followed by PPSV23, plus meningococcal vaccines (MenACWY and MenB)
Asplenic patients are at high risk for infections with encapsulated organisms and require pneumococcal, meningococcal (MenACWY and MenB), and Hib vaccines.
A clinic patient tests positive for HCV RNA. What is the preferred treatment regimen for treatment-naïve, non-cirrhotic genotype 1a HCV?
Answer: Glecaprevir/pibrentasvir for 8 weeks
Glecaprevir/pibrentasvir (Mavyret) for 8 weeks is a pangenotypic, guideline-recommended option for treatment-naïve non-cirrhotic HCV patients.
When counseling a patient starting isoniazid (INH) for latent TB, which supplement should be co-prescribed to prevent peripheral neuropathy?
Answer: Pyridoxine (vitamin B6) 25–50 mg daily
Isoniazid inhibits pyridoxine metabolism, increasing neuropathy risk; pyridoxine supplementation is recommended especially in at-risk patients.
A pharmacist is managing HIV PrEP in a patient who is unable to adhere to daily oral therapy. Which alternative is FDA-approved for HIV pre-exposure prophylaxis?
Answer: Cabotegravir extended-release injectable (Apretude) given every 2 months
Cabotegravir long-acting injectable (Apretude) is FDA-approved for PrEP administered as an injection every 2 months after initial loading doses.