B.Pharm. Bachelor of Pharmacy Bachelor of Pharmacy (B.Pharm.) Pharmaceutics 2

Question 1

Which rheological property describes a fluid whose viscosity decreases under shear stress but recovers when stress is removed?

Accepted Answer

Thixotropy

Answer

Thixotropy refers to a reversible, time-dependent decrease in viscosity upon application of shear stress.

Question 2

The Henderson-Hasselbalch equation is primarily used in pharmacy to calculate:

Accepted Answer

pH of buffer systems

Answer

The Henderson-Hasselbalch equation relates pH, pKa, and the ratio of conjugate base to acid in a buffer.

Question 3

Which type of emulsion is preferred for intravenous administration of lipophilic drugs?

Accepted Answer

Oil-in-water (O/W)

Answer

O/W emulsions place oil droplets in a continuous aqueous phase, making them compatible with blood for IV use.

Question 4

Fick's first law of diffusion states that the rate of drug permeation is directly proportional to:

Accepted Answer

Concentration gradient

Answer

Fick's first law: flux = -D × (dC/dx), showing flux is proportional to the concentration gradient.

Question 5

Supercritical fluid technology using CO₂ is most commonly applied in pharmaceutical manufacturing to:

Accepted Answer

Micronize drug particles

Answer

Supercritical CO₂ is used in particle engineering (RESS, SAS processes) to produce fine, uniform drug particles.

B.Pharm. Bachelor of Pharmacy Practice Test