Blood Banking and Transfusion Flashcards
7 cards from real ABPATH practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Blood Banking and Transfusion flashcards as text
The direct antiglobulin test (DAT) detects which of the following?
Answer: Antibody or complement bound to red cells in vivo
The DAT detects immunoglobulin or complement already coating red cells in vivo.
In the ABO system, which individual is the universal plasma donor?
Answer: Group AB
Group AB plasma lacks anti-A and anti-B, making it the universal plasma donor.
The Rh antigen most commonly implicated in hemolytic disease of the fetus and newborn is:
Answer: D
Anti-D remains the most clinically significant cause of severe HDFN.
What is the purpose of Rh immune globulin (RhIG) administration in an RhD-negative pregnant woman?
Answer: To prevent maternal anti-D alloimmunization from fetal RhD-positive cells
RhIG prevents active immunization by clearing fetal RhD-positive cells before sensitization.
A weak D phenotype is best explained by which molecular mechanism?
Answer: Reduced quantity of complete D antigen on the red cell
Weak D results from a reduced number of otherwise complete D antigen sites.
Which test is used to quantify fetomaternal hemorrhage to calculate the RhIG dose?
Answer: Kleihauer-Betke test
The Kleihauer-Betke test quantifies fetal cells in maternal blood to determine RhIG dosing.
What is the maximum room-temperature storage duration for platelet concentrates with continuous agitation?
Answer: 5 to 7 days
Platelets are stored 5 days (up to 7 with approved testing) at 20-24°C with agitation.