Blood Banking and Transfusion Flashcards
7 cards from real ABPATH practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Blood Banking and Transfusion flashcards as text
A patient's serum reacts with all reagent red cells in an antibody panel including the autocontrol. What is the most likely cause?
Answer: A warm autoantibody
Pan-reactivity with a positive autocontrol typically indicates a warm autoantibody.
Which blood group system antigen is destroyed by treating red cells with proteolytic enzymes like ficin?
Answer: Fya (Duffy)
Duffy antigens (Fya/Fyb) are denatured by proteolytic enzymes such as ficin and papain.
A group O mother delivers a group A infant with a positive DAT and jaundice at birth. What is the most likely diagnosis?
Answer: ABO hemolytic disease of the newborn
Group O mothers produce IgG anti-A,B that crosses the placenta causing ABO HDN.
What is the minimum hemoglobin concentration typically required for an allogeneic whole blood donor in the US?
Answer: 12.5 g/dL
US regulations require a minimum hemoglobin of 12.5 g/dL for allogeneic donors.
A febrile nonhemolytic transfusion reaction is most commonly caused by which mechanism?
Answer: Cytokines from donor leukocytes and recipient antibodies to leukocytes
FNHTRs result from accumulated cytokines and recipient anti-leukocyte antibodies.
Which component is the treatment of choice for fibrinogen replacement in a bleeding patient with hypofibrinogenemia?
Answer: Cryoprecipitate
Cryoprecipitate is rich in fibrinogen and is used to correct hypofibrinogenemia.
At what temperature must red blood cell units be stored during refrigerated storage?
Answer: 1 to 6°C
RBC units are stored refrigerated at 1 to 6°C.