Practice Test GeeksAmerican Board of Pathology (ABPath) Practice Test
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Anatomic Pathology Flashcards

7 cards from real ABPATH practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. Which marker is most useful to identify neuroendocrine differentiation?

    Answer: Synaptophysin

    Synaptophysin (with chromogranin) marks neuroendocrine cells and tumors.

  2. The presence of Charcot-Leyden crystals in tissue suggests:

    Answer: Eosinophil-rich (allergic/parasitic) process

    Charcot-Leyden crystals derive from eosinophils and indicate allergic or parasitic conditions.

  3. Which stain highlights mucin and is often used in adenocarcinomas?

    Answer: Mucicarmine

    Mucicarmine stains epithelial mucin, useful in identifying adenocarcinoma.

  4. A tumor with clear cytoplasm and a delicate 'chicken-wire' vasculature in the kidney is most likely:

    Answer: Clear cell renal cell carcinoma

    Clear cell RCC shows clear cytoplasm and a fine capillary (chicken-wire) network.

  5. Ki-67 immunostaining is used primarily to assess:

    Answer: Proliferative index

    Ki-67 labels proliferating cells and estimates the tumor proliferation index.

  6. Which histologic feature defines squamous cell carcinoma?

    Answer: Keratin pearls and intercellular bridges

    Keratinization (keratin pearls) and intercellular bridges characterize squamous cell carcinoma.

  7. In immunohistochemistry, cytokeratin positivity supports an origin that is:

    Answer: Epithelial

    Cytokeratins are intermediate filaments expressed by epithelial cells and carcinomas.