Anatomic Pathology Flashcards
7 cards from real ABPATH practice questions. Tap to flip, then mark Knew It or Still Learning โ missed cards come back until you master them.
Read the first 7 Anatomic Pathology flashcards as text
Which marker is a sensitive indicator of vascular/endothelial differentiation?
Answer: CD31
CD31 is a highly specific and sensitive endothelial marker used in vascular tumors.
Barrett esophagus is defined histologically by replacement of squamous epithelium with:
Answer: Intestinal-type columnar epithelium with goblet cells
Barrett esophagus shows intestinal metaplasia with goblet cells in the distal esophagus.
Which tumor characteristically shows a 'starry sky' appearance on low power?
Answer: Burkitt lymphoma
Tingible-body macrophages among densely packed cells create the starry sky pattern in Burkitt lymphoma.
Councilman (apoptotic) bodies are typically seen in:
Answer: Viral hepatitis
Councilman bodies are apoptotic hepatocytes seen in viral hepatitis and yellow fever.
Which immunostain is the most widely used marker for gastrointestinal stromal tumors (GIST)?
Answer: CD117 (c-KIT)
Most GISTs express CD117 (c-KIT), reflecting activating KIT mutations.
Caseating granulomas are most characteristic of infection with:
Answer: Mycobacterium tuberculosis
Caseating (necrotizing) granulomas are the hallmark of tuberculosis.
Which stain best demonstrates iron (hemosiderin) in tissue?
Answer: Prussian blue
Prussian blue (Perls) stain highlights iron deposits as blue.