Practice Test GeeksAmerican Board of Pathology (ABPath) Practice Test
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Anatomic Pathology Flashcards

7 cards from real ABPATH practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. Psammoma bodies are most characteristically associated with which thyroid malignancy?

    Answer: Papillary carcinoma

    Psammoma bodies (concentric calcifications) are a classic feature of papillary thyroid carcinoma.

  2. Which immunohistochemical stain is most useful to confirm a diagnosis of prostatic adenocarcinoma by highlighting loss of basal cells?

    Answer: p63

    p63 marks basal cells, which are absent in invasive prostatic adenocarcinoma.

  3. Reed-Sternberg cells are the hallmark of which disease?

    Answer: Classic Hodgkin lymphoma

    Binucleate Reed-Sternberg cells define classic Hodgkin lymphoma.

  4. A frozen section is primarily used intraoperatively to:

    Answer: Assess margins and guide surgical decisions

    Frozen sections give rapid guidance on margins and diagnosis during surgery.

  5. Which stain is used to identify amyloid deposits, showing apple-green birefringence under polarized light?

    Answer: Congo red

    Congo red stains amyloid and produces apple-green birefringence under polarized light.

  6. Signet ring cells are most classically associated with carcinoma of the:

    Answer: Stomach

    Diffuse gastric carcinoma characteristically contains mucin-filled signet ring cells.

  7. Which feature is used to distinguish invasive carcinoma from carcinoma in situ?

    Answer: Breach of the basement membrane

    Invasion requires penetration through the basement membrane into surrounding stroma.