ABD Hair and Nail Disorders Flashcards
6 cards from real ABD practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 ABD Hair and Nail Disorders flashcards as text
Which FDA-approved oral JAK inhibitor was first approved specifically for severe alopecia areata in adults?
Answer: Baricitinib
Baricitinib (Olumiant) received FDA approval in June 2022 as the first systemic treatment specifically indicated for severe alopecia areata in adults.
Lichen planopilaris, a scarring alopecia, characteristically shows which dermoscopic finding?
Answer: Perifollicular scaling and fibrotic white dots
Lichen planopilaris shows perifollicular scaling, loss of follicular openings, and fibrotic white dots (stellate scarring) on dermoscopy.
Terry's nails (proximal white nail with distal pink band) are most commonly associated with which systemic condition?
Answer: Liver cirrhosis
Terry's nails, featuring proximal white discoloration with a 0.5-3mm distal pink or red band, are most commonly associated with liver cirrhosis.
Hailey-Hailey disease (benign familial pemphigus) is caused by mutations in which gene?
Answer: ATP2C1 (hSPCA1)
Hailey-Hailey disease is caused by loss-of-function mutations in ATP2C1 encoding hSPCA1, a Golgi calcium/manganese ATPase pump.
Which beta-blocker class medication is a well-established pharmacologic cause of telogen effluvium?
Answer: Propranolol
Beta-blockers such as propranolol are classic pharmacologic causes of telogen effluvium by shifting hairs prematurely from anagen to telogen phase.
A positive hair pull test is defined as extraction of more than how many hairs from a bundle of 50-60 hairs?
Answer: 6 hairs
A positive pull test is defined as extraction of more than 6 hairs (or >10% of grasped hairs) from a bundle of approximately 50-60 hairs, indicating active shedding.