AMC MCQ Practice Test 2 — Questions and Answers
Question 1: A 58-year-old man presents with crushing central chest pain radiating to the left arm for 40 minutes. ECG shows ST elevation in leads II, III, and aVF. Which artery is most likely occluded?
- Right coronary artery (Correct answer)
- Left anterior descending artery
- Left circumflex artery
- Left main coronary artery
Correct answer: Right coronary artery
ST elevation in the inferior leads (II, III, aVF) typically indicates occlusion of the right coronary artery.
Question 2: A 24-year-old woman with no past history presents with sudden severe headache described as the worst of her life. What is the most appropriate first investigation?
- Non-contrast CT brain (Correct answer)
- Lumbar puncture
- MRI brain
- Cerebral angiography
Correct answer: Non-contrast CT brain
Non-contrast CT brain is the first-line investigation to detect subarachnoid haemorrhage.
Question 3: A 6-month-old infant has a barking cough, stridor, and a low-grade fever. What is the most likely diagnosis?
- Croup (laryngotracheobronchitis) (Correct answer)
- Epiglottitis
- Bronchiolitis
- Foreign body aspiration
Correct answer: Croup (laryngotracheobronchitis)
Barking cough with stridor and mild fever is the classic presentation of viral croup.
Question 4: A 65-year-old smoker presents with progressive dyspnoea and a chronic productive cough. Spirometry shows FEV1/FVC of 0.6 with minimal bronchodilator reversibility. What is the diagnosis?
- Chronic obstructive pulmonary disease (Correct answer)
- Asthma
- Idiopathic pulmonary fibrosis
- Bronchiectasis
Correct answer: Chronic obstructive pulmonary disease
An FEV1/FVC below 0.7 with minimal reversibility in a smoker indicates COPD.
Question 5: A 30-year-old woman presents with weight loss, heat intolerance, palpitations, and a fine tremor. Which finding most strongly suggests Graves disease specifically?
- Exophthalmos (Correct answer)
- Tachycardia
- Weight loss
- Warm peripheries
Correct answer: Exophthalmos
Exophthalmos (thyroid eye disease) is specific to Graves disease among causes of hyperthyroidism.
Question 6: A 45-year-old man with type 2 diabetes has a HbA1c of 9.2% despite maximal metformin. Which is the most appropriate next step considering cardiovascular benefit?
- Add an SGLT2 inhibitor (Correct answer)
- Add a sulfonylurea
- Switch to insulin alone
- Add acarbose
Correct answer: Add an SGLT2 inhibitor
SGLT2 inhibitors lower glucose while providing proven cardiovascular and renal benefit.
Question 7: A 22-year-old returns from a malaria-endemic region with cyclical fevers, rigors, and splenomegaly. What is the most appropriate diagnostic test?
- Thick and thin blood films (Correct answer)
- Blood culture
- Chest X-ray
- Stool microscopy
Correct answer: Thick and thin blood films
Thick and thin blood films remain the gold standard for diagnosing and speciating malaria.
A 58-year-old man presents with crushing central chest pain radiating to the left arm for 40 minutes.
ECG shows ST elevation in leads II, III, and aVF.
Which artery is most likely occluded?