ALAT Ethics in Animal Research 2

Question 1

Who first formally proposed the Three Rs framework for ethical animal use?

Accepted Answer

William Russell and Rex Burch in 1959

Answer

Peter Singer in 1975

Answer

Jeremy Bentham in 1789

Answer

Jane Goodall in 1986

Question 2

What is Reduction in the context of the Three Rs?

Accepted Answer

Using methods that minimize the number of animals needed for reliable results

Answer

Reducing animal housing size

Answer

Reducing the budget

Answer

Reducing the number of researchers

Question 3

What ethical principle requires that animal pain be minimized unless scientifically justified?

Accepted Answer

Minimizing harm (Refinement)

Answer

Informed consent

Answer

Double-blind methodology

Answer

Supply and demand

Question 4

What is the ethical basis for requiring alternatives searches before approving protocols?

Accepted Answer

To ensure non-animal methods are used when they can replace, reduce, or refine animal use

Answer

To reduce costs

Answer

To delay projects

Answer

To promote competition

Question 5

What ethical responsibility do animal care technicians have regarding welfare concerns?

Accepted Answer

An ethical and legal obligation to report through proper channels with retaliation protection

Answer

No responsibility

Answer

Responsibility only if they caused the problem

Answer

Obligation to report only to direct supervisor

Question 6

What is Replacement as applied to the Three Rs?

Accepted Answer

Substituting non-animal methods or lower species when scientific objectives can still be met

Answer

Replacing old equipment

Answer

Replacing one research team with another

Answer

Replacing animals that die during study