AGD Oral Pathology and Diagnosis 3

Question 1

A 35-year-old woman presents with painful oral ulcers, skin blistering, and a positive Nikolsky sign. Direct immunofluorescence shows intercellular IgG deposits in a 'chicken-wire' pattern. What is the diagnosis?

Accepted Answer

Pemphigus vulgaris

Answer

Pemphigus vulgaris features intraepithelial acantholysis with intercellular IgG and C3 deposits in a chicken-wire pattern on direct immunofluorescence and a positive Nikolsky sign.

Question 2

Which of the following describes the radiographic appearance of a periapical cemento-osseous dysplasia in its mature stage?

Accepted Answer

Mixed radiolucent-radiopaque lesion with a radiolucent rim

Answer

Mature cemento-osseous dysplasia appears as a predominantly radiopaque mass with a thin radiolucent rim, distinguishing it from condensing osteitis or hypercementosis.

Question 3

A patient presents with lip swelling, facial nerve palsy, and fissured tongue. This triad is diagnostic of which condition?

Accepted Answer

Melkersson-Rosenthal syndrome

Answer

Melkersson-Rosenthal syndrome is characterized by the classic triad of recurrent orofacial edema, relapsing facial nerve paralysis, and lingua plicata (fissured tongue).

Question 4

Histologically, which feature differentiates a traumatic (solitary) bone cyst from other jaw cysts?

Accepted Answer

Absence of an epithelial lining with thin fibrous connective tissue wall

Answer

Traumatic bone cysts lack an epithelial lining; the cavity is empty or contains scant serosanguineous fluid with a thin fibrous connective tissue wall.

Question 5

Which of the following salivary gland neoplasms is characterized histologically by cribriform 'Swiss cheese' spaces filled with basophilic mucoid material and perineural invasion?

Accepted Answer

Adenoid cystic carcinoma

Answer

Adenoid cystic carcinoma is known for its cribriform pattern with pseudocysts containing basophilic glycosaminoglycans, high rate of perineural invasion, and propensity for late distant metastasis.

(AGD) Academy of General Dentistry Certification Practice Test

(AGD) Academy of General Dentistry Certification Practice Test

AGD Oral Pathology and Diagnosis 3