AGD Dental Pharmacology 2

Question 1

What is the first-line antibiotic for treating odontogenic infections in patients without penicillin allergy?

Accepted Answer

Amoxicillin

Answer

Amoxicillin is the drug of choice for odontogenic infections due to its broad spectrum, excellent oral bioavailability, good bone penetration, and low toxicity.

Question 2

Metronidazole is particularly effective in treating periodontal and odontogenic infections because it is active against:

Accepted Answer

Strict anaerobic microorganisms

Answer

Metronidazole specifically targets strict anaerobes, which are the predominant pathogens in periodontal disease and many odontogenic infections.

Question 3

Which antibiotic causes permanent intrinsic staining of developing teeth when administered to children under age 8?

Accepted Answer

Tetracycline

Answer

Tetracycline chelates calcium ions in mineralizing tissues, permanently incorporating into dentin and enamel and causing yellow-brown discoloration.

Question 4

Clavulanic acid is added to amoxicillin (Augmentin) primarily because it:

Accepted Answer

Inhibits bacterial beta-lactamase enzymes

Answer

Clavulanic acid is a beta-lactamase inhibitor that protects amoxicillin from enzymatic degradation by resistant bacteria, restoring its antibacterial activity.

Question 5

Clindamycin exerts its antibacterial effect by:

Accepted Answer

Binding to the 50S ribosomal subunit and inhibiting protein synthesis

Answer

Clindamycin binds to the 50S ribosomal subunit, blocking translocation and inhibiting bacterial protein synthesis, making it primarily bacteriostatic.

(AGD) Academy of General Dentistry Certification Practice Test

(AGD) Academy of General Dentistry Certification Practice Test

AGD Dental Pharmacology 2