A 70-year-old patient who smokes 1 pack per day wants to quit. Which approach has the highest evidence for successful tobacco cessation?
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A
Brief clinician advice alone (less than 3 minutes)
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B
Varenicline (Chantix) pharmacotherapy alone
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C
Combination of behavioral counseling plus pharmacotherapy (varenicline or combination NRT)
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D
Nicotine replacement therapy (NRT) patch alone