Addiction Medicine Co-occurring Disorders & Dual Diagnosis Flashcards

In a patient with schizophrenia and cannabis use disorder, which antipsychotic has the most evidence for reducing cannabis use?

Answer: Clozapine

Clozapine has the strongest evidence among antipsychotics for reducing substance use, including cannabis, in patients with schizophrenia.

When differentiating substance-induced psychosis from primary psychosis, which timeframe is most commonly used for observation after abstinence?

Answer: 4 weeks

DSM-5 guidelines suggest that if psychotic symptoms persist beyond 4 weeks of abstinence, a primary psychotic disorder is more likely.

Which mood stabilizer is considered first-line for bipolar disorder co-occurring with alcohol use disorder?

Answer: Valproate (divalproex)

Valproate (divalproex) has demonstrated efficacy for both bipolar disorder and reduction of alcohol use in patients with co-occurring conditions.

Which anxiety disorder has the highest rate of co-occurrence with substance use disorders?

Answer: Social anxiety disorder

Social anxiety disorder (social phobia) has the highest prevalence among anxiety disorders co-occurring with substance use disorders, as patients often use alcohol or other substances to manage social situations.

A clinician suspects a patient's depression is substance-induced rather than primary. Which finding best supports this conclusion?

Answer: Depressive symptoms that resolve within weeks of abstinence

Resolution of depressive symptoms within weeks of achieving abstinence is the hallmark indicator that depression was substance-induced rather than a primary mood disorder.

Which integrated treatment model delivers mental health and substance use services within the same program and clinical team?

Answer: Integrated dual disorder treatment (IDDT)

Integrated Dual Disorder Treatment (IDDT) is the evidence-based model where mental health and substance use services are provided by the same team in the same setting.