ADAT Oral Pathology & Diagnosis 1

Question 1

Which oral lesion presents as a white patch that cannot be wiped off and is considered a potentially malignant disorder?

Accepted Answer

Leukoplakia

Answer

Leukoplakia is a white patch that cannot be wiped off (unlike candidiasis) and carries a 1–17% risk of malignant transformation, requiring biopsy.

Question 2

A patient presents with multiple painful oral ulcers, a vesicular rash on the hands and feet, and fever. What is the most likely diagnosis?

Accepted Answer

Hand, foot, and mouth disease (HFMD)

Answer

HFMD, caused by Coxsackievirus A16, presents with oral ulcers plus vesicular skin lesions on hands and feet, typically in young children.

Question 3

Ameloblastoma is most commonly found in which location?

Accepted Answer

Posterior mandible in the molar-ramus region

Answer

Approximately 80% of ameloblastomas occur in the mandible, with the molar-ramus region being the most common site.

Question 4

Which radiographic finding is characteristic of a dentigerous cyst?

Accepted Answer

Well-defined unilocular radiolucency surrounding the crown of an unerupted tooth

Answer

A dentigerous cyst forms around the crown of an unerupted tooth, appearing as a well-defined unilocular radiolucency at the cementoenamel junction.

Question 5

A biopsy shows 'squamous epithelium with keratin pearl formation, individual cell keratinization, and intercellular bridges.' What is the diagnosis?

Accepted Answer

Well-differentiated squamous cell carcinoma

Answer

Keratin pearls, individual cell keratinization, and intercellular bridges are classic histologic features of well-differentiated squamous cell carcinoma.

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ADAT Oral Pathology & Diagnosis 1