ADAT Dental Pharmacology

Question 1

Which local anesthetic has the longest duration of action and is most commonly used for prolonged dental procedures?

Accepted Answer

Bupivacaine

Answer

Lidocaine

Answer

Mepivacaine

Answer

Prilocaine

Question 2

What is the maximum safe dose of lidocaine with epinephrine for a healthy adult patient?

Accepted Answer

7.0 mg/kg up to 500 mg

Answer

3.0 mg/kg up to 300 mg

Answer

4.4 mg/kg up to 500 mg

Answer

2.0 mg/kg up to 200 mg

Question 3

Which analgesic is contraindicated in patients with aspirin-exacerbated respiratory disease (AERD)?

Accepted Answer

NSAIDs

Answer

Acetaminophen

Answer

Opioid analgesics

Answer

Gabapentin

Question 4

What is the mechanism of action of penicillin antibiotics?

Accepted Answer

Inhibit bacterial cell wall synthesis by binding PBPs

Answer

Inhibit bacterial DNA gyrase

Answer

Disrupt bacterial cell membrane integrity

Answer

Inhibit bacterial protein synthesis at the 50S ribosome

Question 5

Which drug interaction is most clinically significant when prescribing metronidazole to a dental patient?

Accepted Answer

Disulfiram-like reaction with alcohol

Answer

Antacids reducing absorption

Answer

Reduced efficacy of acetaminophen

Answer

Increased sedation with caffeine

Question 6

Which vasoconstrictors are most commonly combined with local anesthetics in dental cartridges in the US?

Accepted Answer

Epinephrine and levonordefrin

Answer

Phenylephrine and norepinephrine

Answer

Dopamine and epinephrine

Answer

Vasopressin and levonordefrin