ADAT Oral Pathology & Diagnosis 2

Question 1

What is the most common site for oral squamous cell carcinoma (OSCC) in the United States?

Accepted Answer

Lateral and ventral tongue and floor of mouth

Answer

The lateral/ventral tongue and floor of mouth are the most common sites for OSCC in the US, likely due to pooling of carcinogens in saliva at these locations.

Question 2

A patient has recurrent crops of small, round ulcers with a yellow-gray pseudomembrane and erythematous halo that heal without scarring in 7–14 days. What is the diagnosis?

Accepted Answer

Minor aphthous ulcers (recurrent aphthous stomatitis)

Answer

Minor aphthous ulcers are the most common recurrent oral ulceration, characterized by small (<1 cm), round, non-herpetiform ulcers on non-keratinized mucosa that heal without scarring.

Question 3

The Epstein-Barr virus (EBV) is etiologically associated with which oral lesion?

Accepted Answer

Hairy leukoplakia

Answer

Oral hairy leukoplakia is caused by EBV replication in oral epithelial cells, most commonly seen in HIV-positive patients as a white corrugated lesion on the lateral tongue.

Question 4

Which feature most strongly suggests a mucocele rather than a salivary gland tumor?

Accepted Answer

Blue-tinged fluctuant swelling on the lower lip that may rupture and recur

Answer

Mucoceles are blue-tinged, fluctuant, often recurrent lesions on the lower lip caused by mucus extravasation or retention from minor salivary gland trauma.

Question 5

Which bone pathology shows a 'ground glass' radiographic appearance and commonly affects one quadrant of the jaw in young patients?

Accepted Answer

Fibrous dysplasia

Answer

Fibrous dysplasia replaces normal bone with fibrous tissue containing woven bone trabeculae, producing the classic 'ground glass' or 'orange peel' radiographic appearance.

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ADAT Oral Pathology & Diagnosis 2