Acute Care Nurse Practitioner Study Guide 2026

Everything you need to pass the Acute Care Nurse Practitioner exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.

📋 Acute Care Nurse Practitioner Exam Format at a Glance

175
Questions
210 min
Time Limit
70.00%
Passing Score

📚 Acute Care Nurse Practitioner Topics to Study (21)

✍️ Sample Acute Care Nurse Practitioner Questions & Answers

1. Which acid-base disturbance is an expected finding in a patient with permissive hypercapnia during ARDS management?
Respiratory acidosis with partial metabolic compensation

Permissive hypercapnia intentionally allows PaCO₂ to rise; the kidneys partially compensate with bicarbonate retention, producing respiratory acidosis.

2. Please indicate which of the following is not an illustration of a task that a nurse practitioner may delegate to a nursing assistant.
Assessing a patient's signs and symptoms

Assessing a patient's signs and symptoms requires clinical judgment, critical thinking, and a comprehensive understanding of pathophysiology, which are skills within the scope of a licensed nurse (NP or RN). Nursing assistants (NAs) are trained for basic care tasks and cannot perform assessments or provide initial patient education that demands professional nursing judgment. Therefore, assessing a patient's condition is not an appropriate task for delegation to an NA.

3. Which parameter is used to decide between synchronized cardioversion and defibrillation?
Presence of organized QRS complexes

Synchronized cardioversion is used when organized QRS complexes are present (AF, flutter, SVT, VT with pulse); defibrillation is for VF/pulseless VT.

4. Which of the following statements regarding ACE inhibitors, the angiotensin-converting enzyme, is true?
The patient can make up for a skipped dose by taking one as soon as he/she remembers

For most medications, including ACE inhibitors, if a dose is missed, the general advice is to take it as soon as remembered, unless it's almost time for the next scheduled dose. Doubling the next dose is generally discouraged due to the risk of overdose and increased side effects. Patients on ACE inhibitors should also be cautious with activity levels due to potential orthostatic hypotension.

5. Which arrhythmia is the MOST common cause of sudden cardiac arrest in adults?
Ventricular fibrillation

Ventricular fibrillation is the most common initial arrhythmia in sudden cardiac arrest, requiring immediate defibrillation.

6. Which anticoagulation strategy is recommended for acute massive pulmonary embolism (PE) with hemodynamic instability?
Systemic thrombolysis with alteplase + unfractionated heparin

Systemic thrombolysis (alteplase 100 mg IV) plus unfractionated heparin is indicated for massive PE with hemodynamic instability.

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Your Acute Care Nurse Practitioner Study Path
1. Learn with Flashcards → 2. Drill Practice Tests → 3. Take the Full Exam Simulation
Acute Care Nurse Practitioner Study Guide 2026 — Exam Format, Topics & Practice Questions