ACE Study Guide 2026

Everything you need to pass the ACE exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.

📋 ACE Exam Format at a Glance

100
Questions
120 min
Time Limit
80%
Passing Score

📚 ACE Topics to Study (21)

✍️ Sample ACE Questions & Answers

1. What is root cause analysis in ACE quality assurance?
Investigating to find the fundamental underlying cause of a problem

Root cause analysis digs beyond symptoms to find the fundamental cause, enabling corrective actions that prevent recurrence.

2. Which of the following is NOT required for ACE exam registration?
A letter of recommendation

The ACE registration process includes agreeing to the exam terms and paying the fee, but a reference letter is not required.

3. What is the primary purpose of registering a contract pharmacy on the HRSA 340B database?
To make the arrangement official and ensure manufacturers recognize it for 340B pricing

Registering a contract pharmacy on the HRSA 340B OPAIS database makes the arrangement official, enabling the covered entity to purchase 340B drugs dispensed at that location.

4. Which of the following statements about ACE exam scheduling is TRUE?
Candidates schedule the exam via the testing vendor platform

Candidates schedule their ACE exam via the exam vendor's system after completing all required steps on the Apexus platform.

5. Which organization administers the Apexus Certified Expert (ACE) program?
Apexus

Apexus, the HRSA-designated Prime Vendor for the 340B Program, administers the ACE certification and learning modules.

6. A Ryan White HIV/AIDS Program grantee is determining whether a patient qualifies for 340B. Which factor is MOST critical in this determination?
Whether the covered entity maintains the patient's health records and provides ongoing care

Regardless of the type of covered entity, the core patient definition requires an established care relationship with maintained health records and ongoing care responsibility.

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Your ACE Study Path
1. Learn with Flashcards → 2. Drill Practice Tests → 3. Take the Full Exam Simulation