ABPath Blood Banking and Transfusion 4

Question 1

The direct antiglobulin test (DAT) detects which of the following?

Accepted Answer

Antibody or complement bound to red cells in vivo

Answer

Free antibody in the patient's serum

Answer

Platelet antibodies

Answer

Fibrin degradation products

Question 2

In the ABO system, which individual is the universal plasma donor?

Accepted Answer

Group AB

Answer

Group O

Answer

Group A

Answer

Group B

Question 3

The Rh antigen most commonly implicated in hemolytic disease of the fetus and newborn is:

Accepted Answer

D

Answer

c

Answer

E

Answer

Cw

Question 4

What is the purpose of Rh immune globulin (RhIG) administration in an RhD-negative pregnant woman?

Accepted Answer

To prevent maternal anti-D alloimmunization from fetal RhD-positive cells

Answer

To treat existing anti-D antibodies

Answer

To raise the mother's hemoglobin

Answer

To prevent ABO incompatibility

Question 5

A weak D phenotype is best explained by which molecular mechanism?

Accepted Answer

Reduced quantity of complete D antigen on the red cell

Answer

Complete absence of the RHD gene

Answer

An acquired B antigen

Answer

Presence of anti-D

Question 6

Which test is used to quantify fetomaternal hemorrhage to calculate the RhIG dose?

Accepted Answer

Kleihauer-Betke test

Answer

Direct antiglobulin test

Answer

Osmotic fragility test

Answer

Coombs cross-match

Question 7

What is the maximum room-temperature storage duration for platelet concentrates with continuous agitation?

Accepted Answer

5 to 7 days

Answer

24 hours

Answer

21 days

Answer

42 days