ABPath Blood Banking and Transfusion 3

Question 1

A patient develops sudden hypotension, back pain, and hemoglobinuria minutes after starting a transfusion. What is the most likely reaction?

Accepted Answer

Acute hemolytic transfusion reaction

Answer

Allergic reaction

Answer

TRALI

Answer

Febrile nonhemolytic reaction

Question 2

Transfusion-related acute lung injury (TRALI) is characterized by which finding?

Accepted Answer

Non-cardiogenic pulmonary edema within 6 hours of transfusion

Answer

Volume overload with elevated BNP

Answer

Delayed hemolysis at 7 days

Answer

Isolated urticaria

Question 3

Which patients require irradiated cellular blood products to prevent transfusion-associated graft-versus-host disease?

Accepted Answer

Severely immunocompromised and intrauterine transfusion recipients

Answer

All group O recipients

Answer

Patients with sickle cell trait

Answer

Healthy adult trauma patients

Question 4

A delayed hemolytic transfusion reaction most often results from an anamnestic response to which antibody type?

Accepted Answer

Kidd (anti-Jka) antibodies

Answer

Anti-A

Answer

Anti-Lewis

Answer

Anti-P1

Question 5

What is the expected corrected count increment purpose when transfusing platelets?

Accepted Answer

To assess platelet transfusion response and detect refractoriness

Answer

To measure red cell survival

Answer

To evaluate fibrinogen levels

Answer

To check for ABO antibodies

Question 6

Which anticoagulant-preservative allows RBC storage for up to 42 days?

Accepted Answer

CPDA-1 with additive solution (AS)

Answer

CPD alone

Answer

Heparin

Answer

ACD-A

Question 7

A patient with a history of anaphylactic transfusion reactions and undetectable IgA most likely needs which product?

Accepted Answer

Washed or IgA-deficient components

Answer

Irradiated platelets

Answer

Leukoreduced plasma only

Answer

Fresh frozen plasma