ABA ABA Pharmacology & Drug Management 1

Question 1

Which volatile anesthetic has the lowest blood-gas partition coefficient, resulting in the fastest induction and emergence?

Accepted Answer

Desflurane

Answer

Desflurane has the lowest blood-gas partition coefficient (0.45) among commonly used volatile agents, allowing the fastest equilibration and emergence.

Question 2

A patient receives succinylcholine and develops masseter spasm followed by generalized rigidity and a rising temperature. The FIRST drug to administer is:

Accepted Answer

Dantrolene

Answer

Dantrolene inhibits ryanodine receptor-mediated calcium release from the sarcoplasmic reticulum and is the definitive treatment for malignant hyperthermia.

Question 3

The MAC (minimum alveolar concentration) of a volatile anesthetic is DECREASED by which of the following?

Accepted Answer

Opioid premedication

Answer

Opioid premedication reduces MAC by providing analgesia and CNS depression, decreasing the requirement for volatile agent.

Question 4

Which neuromuscular blocking agent is MOST appropriate for a patient with a known history of pseudocholinesterase deficiency?

Accepted Answer

Atracurium

Answer

Atracurium undergoes Hofmann elimination and ester hydrolysis independent of pseudocholinesterase, making it safe in pseudocholinesterase deficiency.

Question 5

Which opioid is MOST likely to cause chest wall rigidity ('wooden chest syndrome') when given as a rapid IV bolus?

Accepted Answer

Fentanyl

Answer

Fentanyl and other synthetic opioids given rapidly IV can cause truncal rigidity, likely via mu-receptor activation in the basal ganglia.

(ABA) ASA (American Society of Anesthesiologists) Board Certification Practice Test

(ABA) ASA (American Society of Anesthesiologists) Board Certification Practice Test

ABA ABA Pharmacology & Drug Management 1