AACC Hematology & Coagulation

Question 1

What is the normal reference range for hemoglobin in adult males?

Accepted Answer

13.5–17.5 g/dL

Answer

The normal hemoglobin range for adult males is 13.5–17.5 g/dL, reflecting their higher red cell mass compared to females.

Question 2

Which hematologic parameter directly measures the average volume of individual red blood cells?

Accepted Answer

MCV

Answer

Mean corpuscular volume (MCV) measures the average size of red blood cells in femtoliters (fL) and is used to classify anemias as microcytic, normocytic, or macrocytic.

Question 3

A patient's CBC reveals MCV of 70 fL, decreased serum ferritin, and elevated TIBC. Which condition is most consistent with these findings?

Accepted Answer

Iron deficiency anemia

Answer

Iron deficiency anemia presents with low MCV (microcytic), decreased ferritin (depleted iron stores), and elevated TIBC (increased iron-binding capacity due to low saturation).

Question 4

Which white blood cell type normally comprises the largest percentage of circulating leukocytes in a healthy adult?

Accepted Answer

Neutrophils

Answer

Neutrophils account for 50–70% of circulating white blood cells and serve as the primary defense against bacterial infections.

Question 5

What is the primary function of platelets in the hemostatic process?

Accepted Answer

Forming the initial platelet plug at sites of vascular injury

Answer

Platelets adhere to damaged subendothelial collagen, activate, and aggregate to form the primary platelet plug, initiating primary hemostasis.

AACC - American Association for Clinical Chemistry Certification Practice Test

AACC - American Association for Clinical Chemistry Certification Practice Test

AACC Hematology & Coagulation