A patient on home TPN through a tunneled CVC spikes a fever. Blood cultures are drawn and the catheter is retained. After 72 hours, cultures remain positive for Candida albicans. What is the correct management?
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A
Continue antifungal therapy and retain the catheter
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B
Remove the catheter and initiate antifungal therapy for at least 14 days after last positive culture
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C
Switch to oral fluconazole and observe
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D
Perform antibiotic lock therapy with antifungal agent