How Long Does Unity Gender Test Take? Complete Guide to Unity Test Results, Timeline & Pregnancy Testing

How long does unity gender test take? Get unity test results in 3-5 days. Full guide to BillionToOne unity test cost, timeline & pregnancy gender testing. 🎯

UnityBy Dr. Lisa PatelAug 23, 202625 min read
How Long Does Unity Gender Test Take? Complete Guide to Unity Test Results, Timeline & Pregnancy Testing

If you're wondering how long does the Unity gender test take, the answer is typically 3 to 5 business days after BillionToOne's laboratory receives your blood sample. The Unity test, developed by BillionToOne, is a next-generation prenatal screening tool that analyzes cell-free DNA from a simple maternal blood draw. It screens for chromosomal conditions like Down syndrome, trisomy 18, trisomy 13, and sex chromosome abnormalities β€” all while giving expectant parents the option to learn the baby's sex. Understanding the full timeline from blood draw to unity test results helps you plan accordingly and reduce anxiety during the waiting period.

The Unity test stands out from traditional prenatal screenings because it combines carrier screening and NIPT (non-invasive prenatal testing) into a single blood draw. This dual-purpose design means you get more information without the need for multiple appointments or separate lab submissions. BillionToOne's proprietary technology achieves high sensitivity and specificity, making it one of the most trusted prenatal panels available in the United States today. The test can be ordered as early as 10 weeks of gestation, making it one of the earliest available options for expectant parents seeking answers about fetal health and gender.

Many parents are surprised to learn that the Unity gender test timeline depends on several factors beyond just laboratory processing. Shipping time from your OB-GYN or maternal-fetal medicine clinic to the BillionToOne lab in Menlo Park, California, can add one to two business days. Weekend and holiday delays also affect turnaround time.

If your sample is drawn on a Thursday afternoon, for example, it may not arrive at the lab until Monday, pushing your results to the following week. Being aware of these logistics helps set realistic expectations and prevents unnecessary worry when results don't appear in your patient portal on day three.

The Unity complete test encompasses two major screening categories: NIPT for fetal chromosomal abnormalities and carrier screening for serious genetic conditions like cystic fibrosis, spinal muscular atrophy, and fragile X syndrome. This comprehensive approach means the results package you receive covers a wide spectrum of potential genetic concerns simultaneously.

The gender result, if you opt in, is typically one of the first components to appear in your portal β€” often arriving before the full carrier screen analysis is complete. Parents who opt into gender disclosure usually see that result within the standard 3 to 5 business day window once the lab receives the sample.

Cost is another major consideration for families evaluating the Unity test. The billiontoone unity test cost varies depending on insurance coverage, but many plans cover at least the NIPT portion of the panel. Out-of-pocket costs for uninsured patients or those with limited coverage can range from a few hundred dollars to over a thousand dollars for the complete panel.

BillionToOne does offer financial assistance programs, and many patients find that the all-in-one nature of the Unity complete test makes it more economical than ordering separate NIPT and carrier screening panels through different laboratories. Always verify your specific benefit with your insurer before ordering.

Receiving your Unity test results can feel like one of the most emotionally charged moments of your pregnancy. Whether you are waiting to learn about chromosomal conditions, carrier status for genetic diseases, or simply eager to find out your baby's sex, it's important to work with your healthcare provider to interpret results correctly.

A positive screen for a chromosomal condition on NIPT does not mean a definitive diagnosis β€” it means further testing, such as amniocentesis or chorionic villus sampling, may be recommended. Conversely, a negative result is highly reassuring but does not guarantee a completely unaffected pregnancy. Your OB-GYN or genetic counselor is your best resource for result interpretation.

Preparation before your blood draw can also influence the overall experience. No fasting is required for the Unity test, and you can take your prenatal vitamins as usual. Make sure your clinic uses the specific BillionToOne collection kit, as non-approved tubes may result in sample rejection and the need for a repeat draw β€” adding days to your timeline.

Confirming with your provider that they have the correct supplies before your appointment is a simple step that prevents significant delays. Tracking your sample using the BillionToOne patient portal can also give you peace of mind as your sample moves through the shipping and processing phases.

Unity Test by the Numbers

⏳3–5 DaysLab Turnaround TimeAfter sample received by BillionToOne
🩸10 WeeksEarliest Gestational AgeMinimum for ordering the Unity test
πŸ“Š>99%Sensitivity for Trisomy 21BillionToOne published performance data
πŸ’°$0–$250Patient Cost (Insured)Varies by plan; financial assistance available
🧬200+Conditions ScreenedCarrier screening + chromosomal NIPT combined
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Unity Test Timeline: From Blood Draw to Results

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Blood Draw at Your Clinic

Your OB-GYN or midwife collects a maternal blood sample using BillionToOne's approved collection kit at or after 10 weeks gestation. No fasting is required. The draw typically takes less than 10 minutes and is no different from a standard blood test.
πŸ“¦

Sample Shipped to BillionToOne Lab

The clinic ships your sample overnight to BillionToOne's CLIA-certified laboratory in Menlo Park, California. Shipping typically takes 1 to 2 business days. Weekend and holiday pickups may delay arrival, so timing your draw to earlier in the week is advisable.
πŸ”¬

Lab Receives and Accessions Sample

Upon arrival, the sample is logged into the laboratory information system. Staff verify sample integrity, check collection tube type, and confirm patient demographics. Rejected samples due to incorrect tubes or hemolysis require a repeat draw, restarting the timeline from day one.
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Cell-Free DNA Analysis Performed

BillionToOne's sequencing technology analyzes fetal cell-free DNA circulating in the maternal blood. The NIPT component evaluates chromosomal ratios for trisomies 21, 18, and 13, plus sex chromosomes. The carrier screening panel simultaneously evaluates maternal DNA for recessive condition variants.
πŸ“‹

Results Released to Provider Portal

Results are typically released 3 to 5 business days after sample receipt. Your ordering provider receives results first through their portal. Many clinics then share results with patients via phone call, patient portal message, or scheduled follow-up appointment depending on their disclosure protocol.
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Genetic Counseling & Follow-Up

For any positive or high-risk results, your provider will recommend genetic counseling and may refer you for diagnostic testing. Negative results are reviewed at your next prenatal visit. Gender results, if opted in, are usually discussed at this stage or released directly through the patient portal.

The Unity complete test from BillionToOne is genuinely one of the most comprehensive prenatal panels currently available to patients in the United States. Unlike standard NIPT offerings that focus exclusively on chromosomal abnormalities, the Unity test merges two distinct testing modalities β€” non-invasive prenatal testing and expanded carrier screening β€” into a single maternal blood draw.

This integration means that both the pregnant parent and the fetus are screened simultaneously, giving clinicians and families a much richer picture of potential genetic risks before birth. Understanding what each component screens for helps patients know what to expect when reviewing their full results report.

The NIPT portion of the Unity test screens for the most clinically significant chromosomal abnormalities. Trisomy 21, commonly known as Down syndrome, is among the most frequently tested conditions and represents one of the most common chromosomal causes of intellectual disability in the United States. Trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome) are also included, as both carry serious implications for fetal viability and neonatal health.

Additionally, the Unity test evaluates sex chromosome aneuploidies, including Turner syndrome (monosomy X), Klinefelter syndrome (XXY), and other variants. It is through this sex chromosome analysis that the fetal sex β€” male or female β€” can be determined, giving families who opt in their first glimpse of the baby's biological sex.

The carrier screening portion of the unity test pregnancy gender panel examines the mother's DNA for recessive genetic variants associated with serious childhood-onset conditions. Cystic fibrosis, spinal muscular atrophy (SMA), and fragile X syndrome are among the highest-priority conditions covered. SMA screening is particularly impactful because early identification allows for treatment initiation β€” including gene therapy β€” immediately after birth, dramatically improving outcomes.

The Unity test also screens for sickle cell disease, beta-thalassemia, phenylketonuria, and dozens of other conditions depending on the specific panel version ordered by your provider. Together, these components make Unity one of the most thorough single-draw prenatal tests available.

One important concept for patients to grasp is the difference between carrier status and affected status. If the Unity test identifies you as a carrier for a recessive condition like cystic fibrosis, it means you carry one copy of a disease-causing variant but are typically unaffected yourself. The risk to your baby depends on whether the biological father also carries a variant in the same gene.

If both parents are carriers, each pregnancy has a 25% chance of being affected, a 50% chance of being a carrier, and a 25% chance of being neither. BillionToOne's results reports clearly explain carrier status and recommend partner testing when clinically indicated, streamlining the counseling process for providers.

Fetal fraction is a technical metric that significantly influences the reliability of NIPT results. It refers to the percentage of cell-free DNA in the maternal blood sample that comes from the fetus versus the mother. A fetal fraction below approximately 4% may produce an inconclusive or no-call result, meaning the laboratory cannot confidently report NIPT findings.

Low fetal fraction is more common in early gestation (before 10 weeks), in patients with higher body mass index, and in certain chromosomal conditions where the placenta produces less fetal DNA. BillionToOne's technology is optimized to maximize fetal fraction accuracy, but a repeat draw may occasionally be necessary for samples with insufficient fetal DNA.

Patients frequently ask whether the Unity test results are available faster for gender compared to other components of the panel. In practice, fetal sex determination through sex chromosome analysis is completed as part of the same NIPT sequencing run as the chromosomal abnormality screening. There is no separate processing step that would accelerate or delay the gender result independently.

However, some clinics may report the gender component separately or sooner than the full carrier screening panel if the NIPT and carrier analyses are batched differently internally. Always confirm with your specific ordering provider how and when results will be communicated to avoid confusion.

The Unity NIPT test also evaluates for microdeletions in some panel configurations, including 22q11.2 deletion syndrome (DiGeorge syndrome), which is associated with heart defects, immune problems, and developmental delays. Microdeletion screening adds another layer of clinical value beyond the standard trisomy and sex chromosome panels. Not all providers order the microdeletion add-on, so confirm with your OB-GYN or maternal-fetal medicine specialist whether this expanded component is included in your specific test order. Understanding exactly which components have been ordered prevents surprises when results are released and ensures you are asking the right follow-up questions during your results consultation.

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Unity NIPT Test Results: Understanding Your Report

A negative Unity NIPT result means the test found no evidence of the screened chromosomal abnormalities in the fetal DNA analyzed. For trisomies 21, 18, and 13, a negative result carries a very high negative predictive value β€” meaning it is highly unlikely your baby has one of these conditions. Most expectant parents receive negative results, and this outcome is generally reassuring, allowing the pregnancy to proceed with standard prenatal monitoring. Your provider will review the full negative results report at your next prenatal visit.

It is important to remember that a negative NIPT result does not guarantee a completely healthy baby. NIPT screens for specific chromosomal conditions but does not evaluate for all birth defects, single-gene disorders, or structural abnormalities that may be detected on anatomy ultrasound. A comprehensive prenatal care plan β€” including a second-trimester anatomy scan around 18 to 20 weeks β€” remains essential even after a reassuring Unity result. Genetic counselors emphasize that NIPT is a screening tool, not a diagnostic test, and negative results should be interpreted in that clinical context.

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BillionToOne Unity Test: Pros and Cons

βœ…Pros
  • +Combines NIPT and carrier screening into a single blood draw, reducing clinic visits
  • +Early testing available from 10 weeks gestation, one of the earliest windows in prenatal care
  • +High sensitivity (>99%) for trisomy 21 reduces false negative rates significantly
  • +Gender result included when patient opts in, satisfying a common parental desire early in pregnancy
  • +Screens for 200+ genetic conditions in the carrier screening component, far exceeding standard panels
  • +BillionToOne offers financial assistance programs making the test accessible to more patients
❌Cons
  • βˆ’Out-of-pocket cost can exceed $1,000 for patients without adequate insurance coverage
  • βˆ’3–5 business day turnaround plus shipping can mean 5–8 total calendar days of waiting
  • βˆ’Low fetal fraction can produce no-call results requiring a repeat draw and additional delay
  • βˆ’Positive screens require confirmatory diagnostic testing, adding more time and anxiety
  • βˆ’Not all clinics carry BillionToOne collection kits, limiting geographic availability
  • βˆ’Microdeletion panel is not universally ordered and must be specifically requested by the provider

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Preparing for Your Unity Test: Complete Checklist

  • βœ“Confirm your gestational age is at least 10 weeks before scheduling your blood draw appointment.
  • βœ“Verify your clinic has BillionToOne-approved collection kits before arriving for your draw.
  • βœ“Check your insurance coverage for NIPT and carrier screening benefits to estimate out-of-pocket cost.
  • βœ“Ask your provider whether the microdeletion panel add-on is included in your specific order.
  • βœ“Decide in advance whether you want to receive fetal sex (gender) results and communicate your preference clearly.
  • βœ“Schedule your blood draw earlier in the week (Monday–Wednesday) to avoid weekend shipping delays.
  • βœ“Continue taking prenatal vitamins and eating normally β€” no fasting is required for the Unity test.
  • βœ“Register for the BillionToOne patient portal so you can track sample status and receive results electronically.
  • βœ“Ask your provider how they will communicate results β€” phone call, portal message, or scheduled appointment.
  • βœ“Arrange to have a genetic counselor consultation available if positive or inconclusive results are returned.

Gender Results Often Appear First in Your Portal

For patients who opt into fetal sex disclosure, the gender result from the Unity NIPT test is typically one of the first components released β€” often visible in the BillionToOne patient portal within the standard 3 to 5 business day window. Full carrier screening results may follow one to two days later in some cases, depending on batch processing schedules. If you see a gender result appear before your complete panel is posted, this is normal and not a cause for concern.

Understanding the cost structure of the BillionToOne Unity test is essential for families making prenatal testing decisions, especially as healthcare costs continue to rise. The billiontoone unity test cost varies substantially based on your insurance plan, your deductible status, and whether your insurer classifies the test as medically necessary or elective.

For patients with commercial insurance who have met their deductible, out-of-pocket costs are often minimal β€” sometimes as low as zero dollars. However, patients on high-deductible health plans or those whose insurers do not cover NIPT may face bills ranging from $400 to over $1,500 for the complete Unity panel including carrier screening.

BillionToOne has implemented a transparent pricing model and offers a Patient Assistance Program specifically designed to reduce financial barriers for families who do not have adequate insurance coverage. Under this program, eligible patients may pay a capped out-of-pocket amount regardless of their insurance situation, making the test more accessible to lower-income families. To apply for financial assistance, patients typically submit income documentation through BillionToOne's website or through their ordering provider's office. The application process is straightforward and decisions are usually returned within a few business days of submission.

Insurance coverage for NIPT has expanded significantly over the past several years as clinical evidence supporting its utility has grown. Most major commercial insurers, including Aetna, Cigna, UnitedHealthcare, and Blue Cross Blue Shield plans, cover NIPT for patients who meet clinical criteria β€” typically defined as advanced maternal age (35 or older at delivery), a personal or family history of chromosomal abnormalities, or an abnormal first-trimester screening result.

For patients under 35 without specific risk factors, coverage is less consistent and requires prior authorization at many plans. The carrier screening component of Unity may be covered under a separate benefit category, such as diagnostic genetic testing, which adds complexity to the billing process.

When your provider submits a claim for the Unity test, two to three separate CPT codes are typically used β€” one for the NIPT analysis, one for the carrier screening panel, and potentially a third for microdeletion testing if ordered. Each code may be adjudicated differently by your insurer, meaning you could receive multiple Explanation of Benefits documents at different times.

Reviewing each EOB carefully and comparing it against BillionToOne's itemized statement helps you identify any billing discrepancies before paying. If you believe a claim was denied in error, BillionToOne's billing department is known to be proactive in assisting patients with appeals.

For patients paying out of pocket, it is worth knowing that BillionToOne publishes a cash-pay price list upon request. Cash-pay patients sometimes receive a discounted rate compared to the standard insurance-billed amount because the billing overhead is lower. Some families also use Health Savings Accounts (HSA) or Flexible Spending Accounts (FSA) to pay for NIPT and carrier screening, as these tests generally qualify as medical expenses under IRS guidelines. Checking with your benefits administrator before your draw can help you maximize pre-tax dollars and reduce your effective cost significantly.

Comparing the Unity test cost to ordering separate NIPT and carrier screening panels through different laboratories often reveals that the Unity complete test is cost-competitive and sometimes less expensive overall. When ordered separately, two panels may trigger two separate deductibles or two separate out-of-pocket maximums depending on how your insurer processes the claims. Unity's single-draw, single-lab model simplifies billing and frequently results in a single Explanation of Benefits document rather than two, making the administrative burden far lower for both patients and providers. This efficiency is one reason many maternal-fetal medicine practices have made Unity their preferred prenatal screening platform.

Finally, it is important to ask about the cost implications of a repeat draw if your first sample produces a no-call result. In most cases, BillionToOne does not charge an additional laboratory fee for the first repeat draw when the no-call was due to technical factors outside the patient's control. However, shipping and clinic fees for the repeat appointment may still apply. Clarifying this policy with both BillionToOne and your clinic before your initial draw helps you budget appropriately and avoids unwelcome surprise charges if a repeat becomes necessary during your prenatal journey.

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The accuracy of the Unity gender test is one of its most compelling features for expectant parents who choose to opt into fetal sex disclosure. BillionToOne reports a sensitivity and specificity of greater than 99% for fetal sex determination when fetal fraction is adequate and the pregnancy is at or beyond 10 weeks gestation.

This accuracy level means that false gender results β€” being told male when the baby is female, or vice versa β€” are exceedingly rare. However, rare does not mean impossible, and patients should understand that the result is a highly accurate statistical prediction rather than an absolute biological certainty until confirmed after birth or through diagnostic testing.

The mechanism behind fetal sex determination in the Unity test is the detection of Y chromosome sequences in the maternal blood sample. If Y chromosome-derived cell-free DNA is detected at a statistically significant level, the fetus is reported as male. If Y chromosome sequences are absent or below the detection threshold, the fetus is reported as female.

This method is highly reliable in singleton pregnancies but becomes more complex in specific scenarios. Vanishing twin syndrome, where one embryo from a multiple pregnancy resorbs early, can result in Y chromosome DNA being present even when only one fetus β€” potentially female β€” remains, creating a potential false male result.

Other rare scenarios that can complicate gender determination include maternal chromosomal conditions affecting the sex chromosomes, recent bone marrow transplants from a male donor (which can introduce male DNA into the maternal bloodstream), and very low fetal fractions. BillionToOne's laboratory team is trained to flag samples that may be affected by these confounding factors, and the results report includes notation about any limitations in the specific analysis. If you have a complex medical history involving any of these factors, discussing them proactively with your ordering provider ensures that your results are interpreted appropriately from the start.

For twin pregnancies, the Unity test can still provide chromosomal risk assessment, but fetal sex determination is more nuanced. In dichorionic-diamniotic (DCDA) twins, if Y chromosome sequences are detected, at least one twin is male β€” but the sex of each individual twin cannot be definitively assigned through NIPT alone.

Monochorionic twins share a placenta, meaning the fetal fraction comes from both fetuses simultaneously, making individual attribution even more complex. Parents of twins eager to learn gender should discuss the limitations of NIPT-based sex determination with their maternal-fetal medicine provider and may need to rely on ultrasound anatomy for individual gender identification.

Many parents also wonder whether the Unity gender test can be used to select the sex of embryos for family balancing purposes. It is important to clarify that the Unity test is a prenatal screening tool for ongoing pregnancies, not a preimplantation genetic testing (PGT) tool for IVF cycles. It detects fetal sex after conception has occurred and the pregnancy is established.

Preimplantation genetic testing for sex selection is a separate, ethically complex area of reproductive medicine. Using prenatal NIPT results for the purpose of pregnancy termination based solely on fetal sex is considered medically and ethically inappropriate by professional organizations including ACOG and SMFM.

The billiontoone unity test gender result, once released, can be shared with family members at the parent's discretion through a gender reveal event, a private conversation, or a sealed envelope from the provider. Some clinics offer to hold the gender result in a sealed envelope for patients who prefer a surprise reveal later in pregnancy while still having the NIPT chromosomal results available for medical decision-making.

This hybrid approach β€” medical use of the full result now, social gender reveal later β€” is an option worth discussing with your provider if you want the best of both worlds. Confirming the logistics of this arrangement in advance prevents the gender result from being inadvertently disclosed before you are ready.

The growing popularity of early gender determination through NIPT reflects a broader cultural shift in prenatal care toward greater information, earlier engagement, and personalized pregnancy experiences. As the Unity test continues to evolve β€” with BillionToOne regularly updating their panel, improving detection algorithms, and expanding condition coverage β€” expectant parents can expect even more comprehensive and accurate results in future versions. Staying informed about what your specific panel version covers, and what it does not, remains the best way to use these powerful tools appropriately and to enter the results conversation with your provider feeling prepared and confident.

Maximizing the value of your Unity test experience requires proactive engagement at every stage of the process, from the moment you discuss testing with your provider to the day you review your results. Start by clearly communicating your goals to your OB-GYN or midwife: do you want only chromosomal risk information, or do you also want carrier screening for both yourself and potentially your partner?

Do you want to know the baby's sex? Are you interested in microdeletion screening? Having these conversations early ensures your provider orders the correct panel components so nothing is omitted and no retroactive add-ons are needed later, which could require a second blood draw.

If you are using a high-risk OB or maternal-fetal medicine practice, your provider may have specific protocols for how Unity results are communicated. Some MFM practices require all results β€” positive or negative β€” to be discussed in a scheduled telehealth or in-person appointment rather than through a patient portal.

Understanding this protocol in advance prevents frustration when you can see that results are available in your portal but your provider has not yet called. Proactively scheduling a results appointment at the time of your blood draw is a simple strategy that reduces the time between result availability and actual discussion, especially for anxious patients.

Partner testing for carrier screening is an often-overlooked dimension of the Unity test workflow. When the Unity test identifies you as a carrier for a recessive condition, BillionToOne typically generates a partner testing recommendation letter that your provider can share with your partner's physician.

Partner testing can be ordered through a simple saliva or blood draw and is often covered by insurance as a follow-up to a positive carrier screen. Completing partner testing promptly β€” rather than waiting until late in pregnancy β€” ensures that counseling and birth planning can occur with maximum lead time if both partners are found to carry variants in the same gene.

Tracking your sample through the BillionToOne online portal gives you real-time visibility into where your sample is in the processing pipeline. After your clinic ships the sample, you can log into the portal to see when it arrives at the lab, when processing begins, and when results are finalized.

This transparency reduces the impulse to call your clinic repeatedly for status updates. If your portal shows that the sample arrived at the lab and more than 7 business days have passed without results, that is an appropriate trigger for a phone call to either your clinic or BillionToOne's customer support line to investigate whether there was a processing issue.

For patients who receive positive or elevated-risk results, accessing genetic counseling promptly is critical to making informed decisions within the relevant clinical windows. Genetic counselors are master's-prepared specialists who provide non-directive counseling β€” meaning they present information objectively without steering patients toward a particular decision. Many health systems now offer telehealth genetic counseling appointments, making access significantly easier than it was even five years ago. BillionToOne's website also maintains a genetic counselor locator tool that patients can use to find a counselor in their area or via telehealth if their provider does not have one on staff.

Documenting your Unity test results and keeping a copy in a personal health file is a practical step that many patients overlook. Prenatal test results are part of your permanent medical record, but having your own copy ensures you can share them with future providers, especially if you change OBs, relocate during pregnancy, or deliver at a hospital different from where you received prenatal care.

The BillionToOne patient portal allows results to be downloaded as a PDF, making archiving straightforward. Your results β€” including gender, chromosomal screening findings, and carrier status β€” may also be clinically relevant in future pregnancies, so retaining them in your personal health records is genuinely worthwhile for long-term healthcare planning.

Finally, remember that the Unity test is one component of a comprehensive prenatal care program, not a substitute for ongoing clinical monitoring. Regular prenatal visits, anatomy ultrasounds, glucose screening, group B strep testing, and other standard elements of prenatal care remain essential regardless of your Unity test results.

A negative Unity screen is reassuring but does not replace the anatomy scan as the primary tool for detecting structural birth defects. Viewing the Unity test as a powerful addition to β€” rather than a replacement for β€” your full prenatal care team gives you the most complete and accurate picture of your pregnancy's health trajectory from the earliest weeks through delivery.

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About the Author

Dr. Lisa Patel
Dr. Lisa PatelEdD, MA Education, Certified Test Prep Specialist

Educational Psychologist & Academic Test Preparation Expert

Columbia University Teachers College

Dr. Lisa Patel holds a Doctorate in Education from Columbia University Teachers College and has spent 17 years researching standardized test design and academic assessment. She has developed preparation programs for SAT, ACT, GRE, LSAT, UCAT, and numerous professional licensing exams, helping students of all backgrounds achieve their target scores.