Trivium Pharmacology Fundamentals 2 — Questions and Answers
Question 1: Which drug classification is used to reduce fever?
- Antipyretic (Correct answer)
- Antiemetic
- Antifungal
- Anticoagulant
Correct answer: Antipyretic
Antipyretics such as acetaminophen and ibuprofen are used to reduce elevated body temperature.
Question 2: What does the term 'half-life' mean in pharmacology?
- Time for drug concentration in plasma to decrease by 50% (Correct answer)
- Time for a drug to reach peak effect
- Duration of the drug's therapeutic window
- Time required for the body to absorb a drug
Correct answer: Time for drug concentration in plasma to decrease by 50%
Half-life is the time required for the plasma concentration of a drug to be reduced by half.
Question 3: Which route of administration provides the fastest drug absorption?
- Intravenous (Correct answer)
- Sublingual
- Intramuscular
- Oral
Correct answer: Intravenous
Intravenous administration delivers the drug directly into the bloodstream, bypassing absorption entirely.
Question 4: A drug that blocks a receptor without activating it is called a(n):
- Antagonist (Correct answer)
- Agonist
- Synergist
- Potentiator
Correct answer: Antagonist
An antagonist binds to a receptor and blocks it without producing an effect.
Question 5: What is the primary organ responsible for drug metabolism?
- Liver (Correct answer)
- Kidney
- Lungs
- Small intestine
Correct answer: Liver
The liver is the main site of drug metabolism, converting drugs into metabolites via enzymatic reactions.
Question 6: Which term describes an unexpected adverse drug reaction that is not related to the drug's pharmacological action?
- Idiosyncratic reaction (Correct answer)
- Allergic reaction
- Toxic reaction
- Side effect
Correct answer: Idiosyncratic reaction
An idiosyncratic reaction is an abnormal, unpredictable response to a drug unrelated to its known pharmacological effects.
Question 7: What is the term for the minimum drug concentration needed to produce a therapeutic effect?
- Minimum effective concentration (Correct answer)
- Toxic threshold
- Loading dose
- Bioavailability
Correct answer: Minimum effective concentration
The minimum effective concentration (MEC) is the lowest plasma drug level at which a therapeutic response occurs.
Trivium Pharmacology Fundamentals 2
Which drug classification is used to reduce fever?