TB TEST Study Guide 2026
Everything you need to pass the TB TEST exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.
📋 TB TEST Exam Format at a Glance
📚 TB TEST Topics to Study (63)
✍️ Sample TB TEST Questions & Answers
1. Where should upper-room ultraviolet germicidal irradiation (UVGI) fixtures be positioned to be most effective in reducing airborne M. tuberculosis?
Upper-room UVGI fixtures are placed in the upper zone so that naturally convecting room air passes through the UV field, killing M. tuberculosis before the air recirculates to the occupied lower zone.
2. A laboratory worker accidentally breaks a vial of live Mycobacterium tuberculosis. Under which regulatory framework must this incident be reported?
M. tuberculosis is a CDC/USDA select agent; laboratory exposure incidents must be reported under the Federal Select Agent Program regulations.
3. Which of the following conditions can cause a false-negative TST result?
Severely immunosuppressed individuals (e.g., HIV with low CD4, on high-dose steroids) may be anergic and unable to mount a delayed hypersensitivity response.
4. Which molecular test is recommended by WHO as the initial diagnostic test for presumptive TB due to its simultaneous detection of M. tuberculosis and rifampicin resistance?
Xpert MTB/RIF is WHO-endorsed as the preferred initial diagnostic test as it simultaneously detects M. tuberculosis DNA and rifampicin resistance mutations within 2 hours.
5. Which of the following best illustrates the concept of 'accountability' as enforced through TB program accreditation?
Accreditation creates structured accountability by requiring facilities to demonstrate ongoing compliance during periodic surveys, with the consequence of conditional status or loss of accreditation for persistent deficiencies.
6. A patient previously treated for active TB disease presents with a positive TST. What is the appropriate interpretation?
TST and IGRA can remain positive after successful TB treatment because immunological memory persists; this does not indicate active disease or treatment failure.