SPEX Assessment Exam Flashcards
7 cards from real SPEX practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 SPEX Assessment Exam flashcards as text
A patient on warfarin is prescribed trimethoprim-sulfamethoxazole for a UTI. What is the most likely drug interaction concern?
Answer: Enhanced anticoagulant effect leading to bleeding risk
TMP-SMX inhibits CYP2C9, the primary enzyme metabolizing warfarin, increasing warfarin levels and bleeding risk.
Which controlled substance schedule includes drugs with accepted medical use but the highest abuse potential?
Answer: Schedule II
Schedule II drugs have accepted medical use but carry the highest abuse potential among approved medications.
A patient with CrCl of 30 mL/min is prescribed metformin. What is the most appropriate pharmacist action?
Answer: Contact the prescriber to discuss discontinuation or alternative
Metformin is contraindicated when CrCl is below 30 mL/min due to risk of lactic acidosis.
Which statement about the Orange Book is most accurate?
Answer: It identifies drug products with established patent and exclusivity information and therapeutic equivalence ratings
The FDA's Orange Book (Approved Drug Products with Therapeutic Equivalence Evaluations) lists therapeutic equivalence ratings and patent/exclusivity data.
A child weighing 22 kg needs amoxicillin for otitis media. The standard pediatric dose is 90 mg/kg/day in 2 divided doses. What is the correct dose per administration?
Answer: 990 mg
90 mg/kg/day × 22 kg = 1980 mg/day ÷ 2 doses = 990 mg per dose.
Which type of medication error involves giving a drug to the wrong patient?
Answer: Wrong-patient error
A wrong-patient error occurs when the correct medication is administered to an unintended patient.
Nitroglycerin sublingual tablets should be stored in which type of container?
Answer: Original manufacturer glass bottle, tightly closed
Nitroglycerin sublingual tablets are highly volatile and must be stored in their original tightly closed glass container to prevent loss of potency.