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Dermatology Flashcards

7 cards from real SPEX practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A patient presents with a well-demarcated, erythematous plaque with silvery scale on the elbow. The Auspitz sign is positive. What is the most likely diagnosis?

    Answer: Psoriasis vulgaris

    Psoriasis vulgaris classically presents with well-demarcated erythematous plaques with silvery scale and a positive Auspitz sign (pinpoint bleeding upon scale removal).

  2. Which dermatophyte is most commonly responsible for tinea capitis in the United States?

    Answer: Trichophyton tonsurans

    Trichophyton tonsurans is the most common cause of tinea capitis in the United States, typically not fluorescing under Wood's lamp.

  3. A 65-year-old man has a pearly, telangiectatic papule on his nose that has slowly enlarged over 2 years. Biopsy shows palisading nuclei at the periphery of tumor islands. What is the diagnosis?

    Answer: Basal cell carcinoma

    Basal cell carcinoma characteristically shows palisading of nuclei at the periphery of tumor nests on histology, with a pearly, telangiectatic clinical appearance.

  4. Which immunofluorescence pattern is characteristic of pemphigus vulgaris?

    Answer: Intercellular IgG in a 'fishnet' pattern

    Pemphigus vulgaris shows intercellular IgG deposition in a 'fishnet' or 'chicken wire' pattern on direct immunofluorescence due to anti-desmoglein antibodies.

  5. A patient with HIV presents with violaceous papules on the hard palate and lower extremities. What is the causative organism?

    Answer: Human herpesvirus 8

    Kaposi sarcoma, which presents with violaceous plaques and papules in immunocompromised patients, is caused by Human herpesvirus 8 (HHV-8).

  6. A 30-year-old woman has butterfly-shaped erythema across her cheeks and nose. ANA is positive. Which skin finding would be most specific for systemic lupus erythematosus?

    Answer: Malar rash sparing the nasolabial folds

    The malar rash of SLE classically spares the nasolabial folds, distinguishing it from rosacea and seborrheic dermatitis.

  7. Which of the following is the preferred treatment for onychomycosis caused by Trichophyton rubrum?

    Answer: Oral terbinafine for 12 weeks

    Oral terbinafine for 12 weeks is the first-line treatment for toenail onychomycosis due to its superior mycological cure rates against dermatophytes.