SCRN Pharmacological Management 3

Question 1

Which medication is contraindicated within 24 hours of IV alteplase administration?

Accepted Answer

Anticoagulants and antiplatelet agents

Answer

Anticoagulants and antiplatelet agents are contraindicated for 24 hours after tPA to reduce the risk of hemorrhagic transformation.

Question 2

A nurse administers 10% of the alteplase dose as an IV bolus over 1 minute. What happens with the remaining 90%?

Accepted Answer

Infused over 60 minutes

Answer

Standard alteplase administration is 10% as an IV bolus over 1 minute and the remaining 90% infused over 60 minutes.

Question 3

Statins are recommended after ischemic stroke primarily because they reduce which risk factor?

Accepted Answer

LDL cholesterol and recurrent stroke risk

Answer

High-intensity statin therapy lowers LDL cholesterol and has been shown to reduce recurrent ischemic stroke and cardiovascular events.

Question 4

A patient with ischemic stroke secondary to carotid artery stenosis is started on dual antiplatelet therapy. Which combination is most commonly used short-term?

Accepted Answer

Aspirin plus clopidogrel

Answer

Short-term dual antiplatelet therapy with aspirin plus clopidogrel is recommended for high-risk TIA or minor stroke to reduce early recurrent events.

Question 5

Which medication is used to treat symptomatic cerebral hypoperfusion (vasospasm) after subarachnoid hemorrhage in addition to nimodipine?

Accepted Answer

Induced hypertension with vasopressors (Triple-H therapy)

Answer

Triple-H therapy (hypertension, hemodilution, hypervolemia) using vasopressors is used to augment cerebral perfusion during symptomatic vasospasm.

(SCRN) Stroke Certified Registered Nurse Practice Test

(SCRN) Stroke Certified Registered Nurse Practice Test

SCRN Pharmacological Management 3