Saudi Prometric Pharmacist Sterile Products and Aseptic Techniques 2

Question 1

What is the key difference between a Biological Safety Cabinet (BSC) and a Laminar Airflow Workbench (LAFW)?

Accepted Answer

A BSC protects the operator from hazardous drug exposure; a LAFW does not

Answer

A BSC uses horizontal airflow; a LAFW uses vertical airflow

Answer

A LAFW has HEPA filtration; a BSC does not

Answer

A BSC is used only for cytotoxics; a LAFW is used for all sterile preparations

Question 2

What is the correct sequence for donning personal protective equipment (PPE) when entering a cleanroom?

Accepted Answer

Shoe covers → head cover → mask → gown → gloves

Answer

Gloves → gown → mask → shoe covers

Answer

Mask → gown → gloves → shoe covers

Answer

Gown → gloves → shoe covers → mask

Question 3

What is the primary purpose of environmental monitoring in a pharmacy cleanroom?

Accepted Answer

To verify ongoing microbiological quality of the compounding environment

Answer

To ensure proper temperature and humidity levels

Answer

To confirm HEPA filter efficiency ratings

Answer

To measure lighting levels for accurate compounding work

Question 4

Why is pyrogen (endotoxin) testing important for parenteral preparations?

Accepted Answer

To detect bacterial cell wall components that cause fever and septic shock

Answer

To confirm the absence of all living microorganisms

Answer

To measure preservative concentration in the preparation

Answer

To verify the osmolality of the injectable solution

Question 5

Which intravenous solution is considered isotonic with human plasma?

Accepted Answer

0.9% sodium chloride (normal saline)

Answer

0.45% sodium chloride (half-normal saline)

Answer

5% dextrose in water (D5W)

Answer

10% dextrose in water

Question 6

How long after first puncture should a multi-dose vial (MDV) be discarded, per standard pharmacy guidelines?

Accepted Answer

28 days

Answer

24 hours

Answer

48 hours

Answer

Until the manufacturer's expiration date

Question 7

Which grade of water is required by pharmacopeial standards for preparing parenteral (injectable) products?

Accepted Answer

Water for Injection (WFI)

Answer

Distilled water

Answer

Purified water

Answer

Sterile drinking water