PTCE Drug Classifications 2

Question 1

Which drug class is primarily used to treat type 2 diabetes by increasing insulin sensitivity in peripheral tissues?

Accepted Answer

Thiazolidinediones

Answer

Thiazolidinediones (e.g., pioglitazone) work as insulin sensitizers by activating PPAR-gamma receptors in adipose and muscle tissue.

Question 2

A patient is prescribed a selective serotonin reuptake inhibitor (SSRI). Which of the following belongs to this class?

Accepted Answer

Sertraline

Answer

Sertraline (Zoloft) is an SSRI; amitriptyline is a TCA, venlafaxine is an SNRI, and bupropion is an NDRI.

Question 3

Which class of antibiotics inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins?

Accepted Answer

Beta-lactams

Answer

Beta-lactams (penicillins, cephalosporins, carbapenems) all inhibit cell wall synthesis by targeting penicillin-binding proteins.

Question 4

Omeprazole is classified as which type of drug?

Accepted Answer

Proton pump inhibitor

Answer

Omeprazole irreversibly inhibits the H+/K+ ATPase proton pump in gastric parietal cells, classifying it as a PPI.

Question 5

Which drug class is contraindicated in patients with a sulfa allergy due to the sulfonamide moiety in its structure?

Accepted Answer

Thiazide diuretics

Answer

Thiazide diuretics contain a sulfonamide group and may cause cross-reactivity in patients with documented sulfa allergies.

(PTCE) Pharmacy Technician Certification Exam Practice Test