PTCE Compounding 3

Question 1

Which ISO class cleanroom is required for the preparation of Category 2 CSPs (compounded sterile preparations)?

Accepted Answer

ISO Class 5

Answer

ISO Class 7

Answer

ISO Class 8

Answer

ISO Class 3

Question 2

What is the maximum BUD for an aqueous oral compounded preparation stored at room temperature under USP <795>?

Accepted Answer

14 days

Answer

30 days

Answer

6 months

Answer

1 year

Question 3

Polyethylene glycol (PEG) suppository bases are classified as which type?

Accepted Answer

Water-soluble base

Answer

Fatty or oleaginous base

Answer

Emulsion base

Answer

Hydrogel base

Question 4

During preparation of a sterile IV admixture, a pharmacy technician must remove air bubbles from a syringe. The best technique is to:

Accepted Answer

Tap the syringe barrel and push the plunger gently to expel bubbles

Answer

Shake the syringe vigorously

Answer

Insert an additional needle to release air

Answer

Allow the syringe to sit upright for 10 minutes

Question 5

Which ointment base is MOST appropriate when the goal is to absorb water and deliver hydrophilic drugs?

Accepted Answer

Absorption base (anhydrous lanolin)

Answer

Hydrocarbon base (petrolatum)

Answer

Water-soluble base (PEG)

Answer

Emulsion base (O/W)

Question 6

A 'clean room' anteroom in a sterile compounding facility is typically maintained at which ISO classification?

Accepted Answer

ISO Class 8

Answer

ISO Class 5

Answer

ISO Class 6

Answer

ISO Class 3

Question 7

Which preservative is commonly used in multi-dose compounded ophthalmic preparations?

Accepted Answer

Benzalkonium chloride (BAK)

Answer

Methylparaben

Answer

Benzyl alcohol

Answer

Thimerosal