PTCE Compounding 2

Question 1

Which beyond-use date (BUD) applies to a non-aqueous compounded preparation stored at room temperature?

Accepted Answer

6 months or the earliest manufacturer expiration date, whichever is sooner

Answer

USP <795> assigns non-aqueous formulations a BUD of 6 months or the earliest component expiration, whichever comes first.

Question 2

What is the primary purpose of a levigating agent in ointment preparation?

Accepted Answer

To reduce particle size and improve uniform distribution of the active ingredient

Answer

Levigating agents (e.g., mineral oil, glycerin) wet and reduce powder particle size before incorporation into an ointment base.

Question 3

A pharmacy technician is preparing a 2% hydrocortisone cream using a 10% hydrocortisone cream and a plain cream base. What compounding method is being used?

Accepted Answer

Geometric dilution

Answer

Geometric dilution involves progressively adding and mixing equal amounts of base to a potent ingredient to ensure uniform distribution.

Question 4

Which USP chapter governs sterile compounding quality standards for pharmacy-prepared products?

Accepted Answer

USP <797>

Answer

USP <797> sets the standards for sterile compounding including environmental monitoring, BUDs, and personnel training.

Question 5

When compounding a suppository using the fusion method, which step is critical to prevent sedimentation of the active drug?

Accepted Answer

Continuously stirring the mixture until it congeals

Answer

Continuous stirring until congealing keeps the active ingredient evenly suspended throughout the suppository base.

(PTCE) Pharmacy Technician Certification Exam Practice Test

(PTCE) Pharmacy Technician Certification Exam Practice Test

PTCE Compounding 2