Compounding Flashcards
7 cards from real PTCE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Compounding flashcards as text
Which ISO class cleanroom is required for the preparation of Category 2 CSPs (compounded sterile preparations)?
Answer: ISO Class 5
All sterile compounding must occur in an ISO Class 5 primary engineering control (PEC), such as a laminar airflow workbench or BSC.
What is the maximum BUD for an aqueous oral compounded preparation stored at room temperature under USP ?
Answer: 14 days
USP limits water-containing oral formulations stored at room temperature to a BUD of 14 days.
Polyethylene glycol (PEG) suppository bases are classified as which type?
Answer: Water-soluble base
PEG bases are water-soluble and dissolve in rectal fluid rather than melting at body temperature.
During preparation of a sterile IV admixture, a pharmacy technician must remove air bubbles from a syringe. The best technique is to:
Answer: Tap the syringe barrel and push the plunger gently to expel bubbles
Tapping and gentle plunger pressure consolidates and expels air from the syringe without compromising sterility.
Which ointment base is MOST appropriate when the goal is to absorb water and deliver hydrophilic drugs?
Answer: Absorption base (anhydrous lanolin)
Absorption bases like anhydrous lanolin can incorporate water and are suitable for hydrophilic active ingredients.
A 'clean room' anteroom in a sterile compounding facility is typically maintained at which ISO classification?
Answer: ISO Class 8
The anteroom where personnel gown and materials are staged is generally maintained at ISO Class 8.
Which preservative is commonly used in multi-dose compounded ophthalmic preparations?
Answer: Benzalkonium chloride (BAK)
BAK is the most widely used preservative in ophthalmic solutions due to its broad-spectrum antimicrobial activity.