Pharmacy Therapeutics 5

Question 1

A patient with gout has a serum uric acid of 9.2 mg/dL and frequent flares. What is the target serum uric acid level with urate-lowering therapy?

Accepted Answer

<6 mg/dL

Answer

<8 mg/dL

Answer

<7 mg/dL

Answer

<5 mg/dL

Question 2

Which antifungal agent works by inhibiting ergosterol synthesis through binding to lanosterol 14α-demethylase?

Accepted Answer

Fluconazole

Answer

Amphotericin B

Answer

Caspofungin

Answer

Nystatin

Question 3

A patient receiving vancomycin develops flushing, erythema, and pruritis over the neck and upper torso during infusion. What is this reaction called and how is it managed?

Accepted Answer

Red man syndrome — slow the infusion rate

Answer

Anaphylaxis — administer epinephrine

Answer

Stevens-Johnson syndrome — discontinue immediately

Answer

Serum sickness — add corticosteroids

Question 4

Which inhaler technique error is most common with dry powder inhalers (DPIs) compared to metered-dose inhalers (MDIs)?

Accepted Answer

Inhaling too slowly

Answer

Inhaling too fast

Answer

Forgetting to shake the device

Answer

Not using a spacer

Question 5

A patient on methotrexate for rheumatoid arthritis is prescribed trimethoprim-sulfamethoxazole for a UTI. What is the primary concern?

Accepted Answer

Additive myelosuppression and folate depletion

Answer

Increased nephrotoxicity

Answer

QT prolongation

Answer

Disulfiram-like reaction

Question 6

Which drug used to treat benign prostatic hyperplasia (BPH) works by blocking 5-alpha reductase and reducing prostate volume over months?

Accepted Answer

Finasteride

Answer

Tamsulosin

Answer

Terazosin

Answer

Sildenafil

Question 7

Which medication used for smoking cessation carries an FDA black box warning for serious neuropsychiatric adverse effects?

Accepted Answer

Varenicline

Answer

Nicotine patch

Answer

Bupropion

Answer

Nortriptyline