Pharmacy Therapeutics 4

Question 1

A patient with heart failure with reduced ejection fraction (HFrEF) is already on an ACE inhibitor and beta-blocker. Which additional agent has been shown to reduce mortality?

Accepted Answer

Spironolactone

Answer

Amlodipine

Answer

Digoxin

Answer

Nitrate alone

Question 2

Which drug interaction is most likely to cause serotonin syndrome?

Accepted Answer

Linezolid + sertraline

Answer

Metoprolol + amlodipine

Answer

Warfarin + aspirin

Answer

Digoxin + amiodarone

Question 3

Which antibiotic class is associated with QT prolongation and is contraindicated in patients with congenital long QT syndrome?

Accepted Answer

Fluoroquinolones

Answer

Penicillins

Answer

Carbapenems

Answer

Tetracyclines

Question 4

A 65-year-old patient is prescribed a statin for primary prevention. Which statin and dose is recommended by ACC/AHA guidelines for moderate-intensity therapy?

Accepted Answer

Atorvastatin 10 mg

Answer

Rosuvastatin 40 mg

Answer

Atorvastatin 40 mg

Answer

Simvastatin 80 mg

Question 5

A patient with Helicobacter pylori-positive peptic ulcer disease is prescribed triple therapy. Which combination is standard first-line treatment?

Accepted Answer

Omeprazole + clarithromycin + amoxicillin

Answer

Omeprazole + metronidazole + tetracycline

Answer

Ranitidine + doxycycline + azithromycin

Answer

Pantoprazole + ciprofloxacin + levofloxacin

Question 6

Which antipsychotic is most associated with metabolic syndrome, including weight gain and dyslipidemia?

Accepted Answer

Olanzapine

Answer

Haloperidol

Answer

Aripiprazole

Answer

Ziprasidone

Question 7

In a patient with acute MI undergoing PCI, dual antiplatelet therapy (DAPT) typically consists of aspirin plus which agent?

Accepted Answer

Clopidogrel or ticagrelor

Answer

Warfarin

Answer

Dipyridamole

Answer

Cilostazol