Pharmacy Therapeutics 3

Question 1

A patient with COPD and chronic stable angina needs a beta-blocker. Which agent is most appropriate?

Accepted Answer

Metoprolol succinate

Answer

Propranolol

Answer

Carvedilol

Answer

Nadolol

Question 2

Clindamycin is used to treat infections caused by which of the following organisms?

Accepted Answer

Methicillin-resistant Staphylococcus aureus (MRSA)

Answer

Pseudomonas aeruginosa

Answer

Enterococcus faecalis

Answer

Klebsiella pneumoniae

Question 3

Which disease-modifying antirheumatic drug (DMARD) requires baseline and periodic ophthalmology exams due to risk of retinal toxicity?

Accepted Answer

Hydroxychloroquine

Answer

Methotrexate

Answer

Leflunomide

Answer

Sulfasalazine

Question 4

A patient presents with opioid overdose. Which reversal agent is administered, and what is its mechanism?

Accepted Answer

Naloxone — opioid receptor antagonist

Answer

Flumazenil — GABA antagonist

Answer

Physostigmine — AChE inhibitor

Answer

Neostigmine — nicotinic agonist

Question 5

A patient with major depressive disorder fails two adequate SSRI trials. What is the most appropriate next step according to treatment guidelines?

Accepted Answer

Switch to an SNRI or add augmentation with atypical antipsychotic

Answer

Add lithium augmentation immediately

Answer

Switch to a different SSRI

Answer

Start ECT

Question 6

Which aminoglycoside dosing strategy is preferred to maximize efficacy and minimize nephrotoxicity?

Accepted Answer

Extended-interval (once-daily) dosing

Answer

Multiple daily dosing (MDD)

Answer

Continuous infusion

Answer

Loading dose only

Question 7

A patient using long-term oral corticosteroids is at risk for which metabolic complication requiring prophylactic treatment?

Accepted Answer

Osteoporosis requiring calcium and vitamin D supplementation

Answer

Hypocalcemia from vitamin D toxicity

Answer

Hyperkalemia requiring potassium restriction

Answer

Hypothyroidism requiring levothyroxine